Results 261 to 270 of about 3,169,653 (411)

IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

Proceedings of the National Academy of Sciences of the United States of America, 2012
F. L. van de Veerdonk, Angela K Stoeckman, Gouping Wu, Aaron N Boeckermann, T. Azam, M. Netea, L. Joosten, J. V. D. van der Meer, Ruyi Hao, V. Kalabokis, C. Dinarello   +10 more
semanticscholar   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Mineralocorticoid Receptor Antagonist Use Among Patients With Chronic Kidney Disease Who Transitioned to Dialysis. [PDF]

Kidney Med
Tong EM, Zhou H, Pak K, Huang CW, Broder BI, Sim JJ.   +5 more
europepmc   +1 more source

Alterations in calcium antagonist receptors and sodium-calcium exchange in cardiomyopathic hamster tissues.

, 1989
John A. Wagner, Harlan F. Weisman, Adele M. Snowman, Ian J. Reynolds, Myron L. Weisfeldt, Solomon H. Snyder   +5 more
openalex   +1 more source

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

Science, 2010
E. Chien, Wei Liu, Qiang Zhao, V. Katritch, Gye Won Han, M. Hanson, Lei Shi, A. Newman, J. Javitch, V. Cherezov, R. Stevens   +10 more
semanticscholar   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Correction to: Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist. [PDF]

Purinergic Signal
Nagel J, Törmäkangas O, Kuokkanen K, El-Tayeb A, Messinger J, Abdelrahman A, Bous C, Schiedel AC, Müller CE.   +8 more
europepmc   +1 more source

A synthetic peptide derivative that is a cholecystokinin receptor antagonist.

, 1987
M. F. Lignon, Marie‐Christine Galas, Mariano Rodríguez, Jeanine Laur, André Aumelas, Jean Martínez   +5 more
openalex   +1 more source

An arylaminopyridazine derivative of gamma-aminobutyric acid (GABA) is a selective and competitive antagonist at the GABAA receptor site. [PDF]

, 1985
J. P. Chambón, P. Feltz, Michel Héaulme, S. Restle, Rémy Schlichter, Kathleen Bizière, Camille G. Wermuth   +6 more
openalex   +1 more source

Identification of Telmisartan as a Unique Angiotensin II: Receptor Antagonist With Selective PPARγ–Modulating Activity

HYPERTENSION, 2004
S. Benson, H. Pershadsingh, Christopher I. Ho, A. Chittiboyina, P. Desai, M. Pravenec, N. Qi, Jiaming Wang, M. Avery, T. Kurtz   +9 more
semanticscholar   +1 more source