Results 121 to 130 of about 403,129 (325)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Increased Expression of Axl Tyrosine Kinase After Vascular Injury and Regulation by G Protein–Coupled Receptor Agonists in Rats [PDF]

, 1998
Matthew G. Melaragno, Daniel Wüthrich, Veronica Poppa, Denzil Gill, Volkhard Lindner, Bradford C. Berk, Marshall A. Corson   +6 more
openalex   +1 more source

Regulation of antigen receptor function by protein tyrosine kinases

Progress in Biophysics and Molecular Biology, 1999
Gabriel Waksman, Andrew C. Chan, Chong Fu, Jane Wong, Juliane Bubeck-Wardenburg, Rajita Pappu, Klaus Fütterer   +6 more
openaire   +3 more sources

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source

Non-receptor protein-tyrosine kinases as molecular targets for antiangiogenic therapy (Review).

International Journal of Molecular Medicine, 2007
S. Kanda, Y. Miyata, H. Kanetake, T. Smithgall   +3 more
semanticscholar   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

, 1991
Masayuki Otsu, I. Hiles, Ivan Gout, Michael Fry, Fernanda Ruiz‐Larrea, George Panayotou, Andrew R. Thompson, Ritu Dhand, J. Justin Hsuan, Nick Totty   +9 more
openalex   +1 more source

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Advanced Healthcare Materials, EarlyView.
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley   +1 more source

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

Cancer Research, 2004
S. Wilhelm, Christopher A. Carter, L. Tang, D. Wilkie, Angela Mcnabola, H. Rong, Charles Chen, Xiaomei Zhang, P. Vincent, M. McHugh, Yichen Cao, Jaleel Shujath, S. Gawlak, Deepa Eveleigh, B. Rowley, Li Liu, Lila Adnane, M. Lynch, D. Auclair, I. Taylor, R. Gedrich, A. Voznesensky, B. Riedl, L. Post, G. Bollag, P. Trail   +25 more
semanticscholar   +1 more source

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.

, 1991
Gary A. Koretzky, Joel Picus, TJ Schultz, A Weiss   +3 more
openalex   +1 more source