Results 161 to 170 of about 396,884 (345)

A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer. [PDF]

Front Oncol
Rangarajan A, Sviezhentseva I, Gunderson E, Pikman Y, Jacobson MP, Apsel Winger B.   +5 more
europepmc   +1 more source

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

Advanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian, Jinxiang Wang, Qiji Li, Yangruiyu Liu, Yanping Chen, Jiacheng Feng, Zi‐Ning Lei, Harsh Patel, Chao‐Yun Cai, Yuzhi Xu, Chuntao Quan, Lingyan Fei, Zexiu Xiao, Shuo Fang, Tianxin Lin, Zhe‐Sheng Chen, Yuchen Liu, Leli Zeng, Yihang Pan   +18 more
wiley   +1 more source

The Role of Tyrosine Kinase in Beauty and Skincare: A Comprehensive Review. [PDF]

J Cosmet Dermatol
Li Z.
europepmc   +1 more source

PDGF Receptor Protein Tyrosine Kinase Expression in the Balloon-Injured Rat Carotid Artery

, 1997
Robert L. Panek, Tawny K. Dahring, Bronia Olszewski, Joan A. Keiser   +3 more
openalex   +1 more source

Protein kinase C isoforms β 1 and β 2 inhibit the tyrosine kinase activity of the insulin receptor [PDF]

, 1997
Birgit Bossenmaier, Luitgard Mosthaf, Harald Mischak, A. Ullrich, Hans‐Ulrich Häring   +4 more
openalex   +1 more source

Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis

Advanced Science, EarlyView.
Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni, Yufei Cui, Mojtaba Salehi, Mui Ling Sharon Nai, Kun Zhou, Cian Vyas, Boyang Huang, Paulo Bartolo   +7 more
wiley   +1 more source

Cracking the Kinase Code: Urinary Biomarkers as Early Alarms for AAA Rupture-A Pilot Study. [PDF]

J Clin Med
Östling EM, Baltrunas T, Grootenboer N, Urbonavicius S.   +3 more
europepmc   +1 more source

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

, 1998
Björn Hock, Beatrix Böhme, Thomas Karn, Takaharu Yamamoto, Kozo Kaibuchi, Uwe Holtrich, Sacha J. Holland, Tony Pawson, Helga Rübsamen‐Waigmann, Klaus Strebhardt   +9 more
openalex   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Advanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S. Yarla, Lu Wang, Jindan Yu, Jonathan C. Zhao, Ivet Bahar, Yong Wan   +14 more
wiley   +1 more source

Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement.

Proceedings of the National Academy of Sciences of the United States of America, 1994
S. J. Saouaf, S. Mahajan, R. Rowley, S. Kut, J. Fargnoli, A. Burkhardt, Satoshi TSUKADAt, Owen N. WITTEt, J. Bolen   +8 more
semanticscholar   +1 more source