Results 171 to 180 of about 167,856 (315)

A Transmembrane Protein WAI‐B2 Confers Multiple Disease Resistance in Wheat by Activating Autoimmunity

Advanced Science, EarlyView.
Wheat production is under threat from multiple diseases. This study clones the wheat autoimmunity gene WAI‐B2 from an EMS‐induced mutant that encodes a distinct transmembrane protein conferring resistance to wheat rusts and powdery mildew ‐ two major diseases affecting wheat crops.
Wenling Li, Yongxing Chen, Lei Dong, Guanghao Guo, Huaizhi Zhang, Tao Shen, Gaojie Wang, Lingli Dong, Ping Lu, Miaomiao Li, Dan Qiu, Keyu Zhu, Beibei Li, Yikun Hou, Xuejia Cui, Baoge Huang, Fugang Yang, Hongkui Fu, Delin Li, Zhan Li, Jinghuang Hu, Yunfeng Qu, Huanhuan Lou, Shisheng Chen, Zaifeng Li, Ling Kang, Wuyun Yang, Chengguo Yuan, Hongjie Li, Yusheng Zhao, Zhiyong Liu, Haiyan Jia, Qiuhong Wu   +32 more
wiley   +1 more source

Targeting Kinase Suppressor of Ras 1 (KSR1) for Cancer Therapy. [PDF]

Pharmaceutics
Moon H, Park H, Lee S, Lee S, Ro SW.
europepmc   +1 more source

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase [PDF]

, 2010
Elina Mattila, Heidi Marttila, Niko Sahlberg, Pekka Kohonen, Siri Tähtinen, Pasi Halonen, Merja Perälä, Johanna Ivaska   +7 more
openalex   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

Advanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
wiley   +1 more source

B-cell receptor signaling and microenvironment crosstalk in mantle cell lymphoma. [PDF]

Cell Commun Signal
Quaglia FM, Gambino S, Galasso M, Vegliante MC, Visco C, Scupoli MT.   +5 more
europepmc   +1 more source

Synergistic Antiproliferative Activity of the RAD51 Inhibitor IBR2 with Inhibitors of Receptor Tyrosine Kinases and Microtubule Protein [PDF]

, 2017
Peter J. Ferguson, Mark Vincent, James Koropatnick   +2 more
openalex   +1 more source

Self‐Assembled Dictamni Cortex Nanoparticles Ameliorate Psoriasis by Epigenetic Modulation of HSP90AB1 and Suppression of the Inflammatory Response

Advanced Science, EarlyView.
This study develops self‐assembled Dictamni Cortex (BXP)‐Fe(III) infinite coordination polymer nanoparticles (NB) to improve BXP's solubility and bioavailability for psoriasis. NB transdermally treats psoriasis by targeting the epigenetic regulator CTCF (CCCTC‐binding factor), suppressing HSP90AB1 (heat shock protein 90 alpha family class B member 1 ...
Zhengyi Zhang, Wenqian Du, Xiaojiang Zhang, Hongbo Cui, Baochen Cheng, Xiao Han, Ke He, Tingyi Yin, Xinyi Liu, Ningyi Xian, Ziyang Wang, Meng Liu, Dan Han, Jiankang Liu, Yan Zheng, Ya Wang   +15 more
wiley   +1 more source

Unbiased kinome profiling identifies key and novel mediators of chronic kidney disease in hyperlipidemic mice. [PDF]

Front Physiol
Bonnin-Marquez A, Maas SL, Corcini-Berndt M, Van der Vorst EPC.   +3 more
europepmc   +1 more source

Examining the Roles of the Receptor Tyrosine Kinase PVR and the Bone Morphogenic Protein Receptor Thickvein in Regulating Self-Renewal and Division Frequency in the Cyst Stem Cells of the Drosophila Testis Niche

, 2019
Nastaran SoleimaniBarzi Mues
openalex   +1 more source

Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells

, 2007
Neil L. Spector, Yosef Yarden, Bradley L. Smith, Ljuba Lyass, Patricia B. Trusk, Karen Pry, Jason E. Hill, Wenle Xia, Rony Seger, Sarah Bacus   +9 more
openalex   +1 more source