Results 271 to 280 of about 293,862 (300)
Some of the next articles are maybe not open access.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1988
On immunoprecipitation using a specific antiphosphotyrosine antibody, phosphatidylinositol kinase (EC 2.7.1.67) activity was separated from the protein-tyrosine kinase (EC 2.7.1.112) activity of the wheat germ agglutinin (WGA) -purified insulin receptor from human placenta.
J M, Carroscosa +4 more
openaire +2 more sources
On immunoprecipitation using a specific antiphosphotyrosine antibody, phosphatidylinositol kinase (EC 2.7.1.67) activity was separated from the protein-tyrosine kinase (EC 2.7.1.112) activity of the wheat germ agglutinin (WGA) -purified insulin receptor from human placenta.
J M, Carroscosa +4 more
openaire +2 more sources
Protein tyrosine kinase receptors.
Cancer surveys, 1997More than 50 PTK receptors are known to be involved in regulation of cell growth, differentiation, chemotaxis and actin reorganization. PTK receptors can be classified into subfamilies according to their structural features. PTK receptors are activated by ligand induced homo- or heterodimerization, which leads to receptor autophosphorylation on ...
openaire +1 more source
Regulation of aryl hydrocarbon receptor signal transduction by protein tyrosine kinases
Cellular Signalling, 2005The involvement of protein tyrosine kinases (PTKs) in aryl hydrocarbon receptor (AhR)-mediated signalling by omeprazole and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was investigated in hepatoma cells. Both omeprazole- and TCDD-dependent AhR signalling was attenuated by inhibition of c-src kinase, either by using pyrazolopyrimidine 4-amino-5-(4 ...
Maria, Backlund +1 more
openaire +2 more sources
Thermal Inactivation of the Protein Tyrosine Kinase of the Epidermal Growth Factor Receptor
Biochemistry, 1996It has been shown previously that the EGF-stimulable protein tyrosine kinase in a membrane preparation from A431 cells was inactivated by heat shock (45 degrees C), under conditions where EGF binding was unaffected [Carpenter et al. (1979) J. Biol. Chem. 254, 4884-4891].
R A, Stein, J V, Staros
openaire +2 more sources
Annexin I as a Potential Inhibitor of Insulin Receptor Protein Tyrosine Kinase
Biochemical and Biophysical Research Communications, 1994Insulin receptor (IR) purified from human placenta by wheat germ agglutinin affinity chromatography was incubated in the presence of insulin, [gamma-32P]ATP and annexin I. In parallel to its own tyrosine phosphorylation, annexin I promoted a dose-dependent inhibition of IR autophosphorylation (IC50 0.5 microM).
V, Melki +5 more
openaire +2 more sources
Reviews in the Neurosciences, 2016
AbstractProtein tyrosine phosphorylation is one of the primary modes of regulation of N-methyl-d-aspartate (NMDA) receptors. The non-receptor tyrosine kinases are one of the two types of protein tyrosine kinases that are involved in this process. The overactivation of NMDA receptors is a primary reason for neuron death following cerebral ischemia. Many
Yongjun, Sun +5 more
openaire +2 more sources
AbstractProtein tyrosine phosphorylation is one of the primary modes of regulation of N-methyl-d-aspartate (NMDA) receptors. The non-receptor tyrosine kinases are one of the two types of protein tyrosine kinases that are involved in this process. The overactivation of NMDA receptors is a primary reason for neuron death following cerebral ischemia. Many
Yongjun, Sun +5 more
openaire +2 more sources
Receptor-Operated Calcium Influx Mediated by Protein Tyrosine Kinase Pathways
Journal of Receptors and Signal Transduction, 1998Calcium influx from the extracellular space elicited by activation of heterotrimeric G protein-coupled and heptahelical receptors plays a critical role in transmembrane signal transduction in a wide variety of cell systems. In nonexcitable cells, the precise voltage-independent mechanism by which calcium enters the cell remains unknown.
openaire +2 more sources
Coupling of the IL2 receptor complex with non-receptor protein tyrosine kinases.
Cancer surveys, 1997IL2 induces the proliferation of T lymphocytes through the IL2 receptor (IL2R) following T lymphocyte activation. The IL2R consists of at least three subunits, IL2R alpha, beta and gamma chains. The cytoplasmic regions of the IL2R beta and gamma chains are critical for transduction of the IL2 signal to the cell interior.
T, Miyazaki, T, Taniguchi
openaire +1 more source
Non-receptor protein tyrosine kinases of normal tissues
International Journal of Biochemistry, 1990openaire +2 more sources