Results 351 to 360 of about 514,942 (384)

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

Science, 1991
Antigen is thought to cross-link membrane-bound immunoglobulins (Igs) of B cells, causing proliferation and differentiation or the inhibition of growth. Protein tyrosine kinases are probably involved in signal transduction for cell proliferation and differentiation. The Src-like protein tyrosine kinase Lyn is expressed preferentially in B cells.
Kumao Toyoshima, Terutaka Kakiuchi, Tadashi Yamamoto, Yuji Yamanashi, Junichiro Mizuguchi   +4 more
openaire   +3 more sources

Thermal Inactivation of the Protein Tyrosine Kinase of the Epidermal Growth Factor Receptor

Biochemistry, 1996
It has been shown previously that the EGF-stimulable protein tyrosine kinase in a membrane preparation from A431 cells was inactivated by heat shock (45 degrees C), under conditions where EGF binding was unaffected [Carpenter et al. (1979) J. Biol. Chem. 254, 4884-4891].
James V. Staros, Richard A. Stein
openaire   +3 more sources

Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist

Biochemical and Biophysical Research Communications, 2008
A panel of 18 protein tyrosine kinase antagonists were tested for their inhibitory effect on human P2X(7) receptor-mediated (86)Rb(+) (K(+)) efflux. The most potent compound (compound P), a phthalazinamine derivative and an inhibitor of vascular endothelial growth factor receptor kinase, blocked ATP-induced (86)Rb(+)-efflux in human B-lymphocytes and ...
Leanne Stokes, Paul W. Manley, Anne N. Shemon, Ronald Sluyter, James S. Wiley   +4 more
openaire   +3 more sources

Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells

Critical reviews in clinical laboratory sciences, 2014
Elżbieta Gocek, A. Moulas, G. P. Studzinski   +2 more
semanticscholar   +1 more source

Expression of the receptor protein‐tyrosine kinases Tyro‐3, Axl, and Mer in the developing rat central nervous system

The Journal of comparative neurology, 2000
A. L. Prieto, J. Weber, Cary Lai
semanticscholar   +1 more source

Signaling by Kit protein-tyrosine kinase—The stem cell factor receptor

Biochemical and Biophysical Research Communications, 2005
Signaling by stem cell factor and Kit, its receptor, plays important roles in gametogenesis, hematopoiesis, mast cell development and function, and melanogenesis. Moreover, human and mouse embryonic stem cells express Kit transcripts. Stem cell factor exists as both a soluble and a membrane-bound glycoprotein while Kit is a receptor protein-tyrosine ...
openaire   +3 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein‐tyrosine kinase

The FASEB Journal, 1995
Susan S. Taylor, E. Radzio‐Andzelm, T. Hunter   +2 more
semanticscholar   +1 more source

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-vornhagen, Victoria Metaxa, Elie Azoulay   +2 more
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul H Parikh
exaly