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Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn
Science, 1991Antigen is thought to cross-link membrane-bound immunoglobulins (Igs) of B cells, causing proliferation and differentiation or the inhibition of growth. Protein tyrosine kinases are probably involved in signal transduction for cell proliferation and differentiation. The Src-like protein tyrosine kinase Lyn is expressed preferentially in B cells.
Kumao Toyoshima+4 more
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Thermal Inactivation of the Protein Tyrosine Kinase of the Epidermal Growth Factor Receptor
Biochemistry, 1996It has been shown previously that the EGF-stimulable protein tyrosine kinase in a membrane preparation from A431 cells was inactivated by heat shock (45 degrees C), under conditions where EGF binding was unaffected [Carpenter et al. (1979) J. Biol. Chem. 254, 4884-4891].
James V. Staros, Richard A. Stein
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Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist
Biochemical and Biophysical Research Communications, 2008A panel of 18 protein tyrosine kinase antagonists were tested for their inhibitory effect on human P2X(7) receptor-mediated (86)Rb(+) (K(+)) efflux. The most potent compound (compound P), a phthalazinamine derivative and an inhibitor of vascular endothelial growth factor receptor kinase, blocked ATP-induced (86)Rb(+)-efflux in human B-lymphocytes and ...
Leanne Stokes+4 more
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Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells
Critical reviews in clinical laboratory sciences, 2014Elżbieta Gocek+2 more
semanticscholar +1 more source
The Journal of comparative neurology, 2000
A. L. Prieto, J. Weber, Cary Lai
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A. L. Prieto, J. Weber, Cary Lai
semanticscholar +1 more source
Signaling by Kit protein-tyrosine kinase—The stem cell factor receptor
Biochemical and Biophysical Research Communications, 2005Signaling by stem cell factor and Kit, its receptor, plays important roles in gametogenesis, hematopoiesis, mast cell development and function, and melanogenesis. Moreover, human and mouse embryonic stem cells express Kit transcripts. Stem cell factor exists as both a soluble and a membrane-bound glycoprotein while Kit is a receptor protein-tyrosine ...
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-vornhagen+2 more
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