Results 111 to 120 of about 334,561 (215)

Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor.

, 1993
Daniel R. Knighton, Deborah L. Cadena, Jie Zheng, Lynn F. Ten Eyck, Susan S. Taylor, Janusz M. Sowadski, Gordon N. Gill   +6 more
openalex   +1 more source

Identification of C-mannosylation in a receptor tyrosine kinase AXL. [PDF]

Glycobiology
Mori K, Suzuki T, Waki U, Hayashi S, Kadono S, Kawahara R, Takeuchi M, Mizuta H, Dohmae N, Katayama R, Simizu S.   +10 more
europepmc   +1 more source

Single‐Cell RNA Sequencing Reveals the Heterogeneity in Differentiation Trajectory and Tumor Microenvironment Leading to More Aggressive Phenotypes of Papillary Thyroid Cancer in Children and Young Adult Patients

Advanced Science, EarlyView.
scRNA sequencing reveals distinct tumor ecosystem features in CAYA‐PTC, marked by enriched CD4T_Tfh, CD8T_Tex cells, and rapid malignant thyrocyte differentiation (absent of mild‐state BRAF‐like population) toward invasive states. Prominent emCAF_LAMP5 populations interact with endothelial cells and thyrocytes facilitate angiogenesis and metastasis ...
Kai Guo, Lingyi Yang, Zirui Huang, Kai Qian, Yuan Shi, Mengjia Fei, Yuan Feng, Zixian Chen, Ming Qiu, Linglin Tang, Anqi Li, Zhibao Lv, Jiangbin Liu, Zhou Chen, Kuiran Dong, Zhuoying Wang   +15 more
wiley   +1 more source

Cell-free expression and SMA copolymer encapsulation of a functional receptor tyrosine kinase disease variant, FGFR3-TACC3. [PDF]

Sci Rep
Snow AJD, Wijesiriwardena T, Lane BJ, Farrell B, Dowdle PC, Katan M, Muench SP, Breeze AL.   +7 more
europepmc   +2 more sources

The dual EGF/VEGF receptor tyrosine kinase inhibitor AEE788 inhibits growth of human hepatocellular carcinoma xenografts in nude mice

, 1992
Matthias Ocker
openalex   +2 more sources

Correction: Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells. [PDF]

Oncotarget
Vouri M, An Q, Birt M, Pilkington GJ, Hafizi S.   +4 more
europepmc   +1 more source

Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos

Advanced Science, EarlyView.
This study performs a comprehensive single‐cell transcriptome analysis of sheep embryos from embryonic (E) day 1 to E14 to elucidate the mechanism of early lineage specification and the pluripotency changes (naïve, formative, and primed) of epiblast.
Jinying Zhang, Runbo Li, Ruijie Luo, Qiang Zhang, Zimo Zhao, Haishen Xu, Minglei Zhi, Wenjie Jiang, Meng Wang, Xinze Chen, Zhiqiang Feng, Yingjie Wang, Yuhan Yang, Pengcheng He, Hanyue Su, Tianzhi Chen, Shunxin Wang, Yixuan Yao, Jinghui Yang, Fan Zhao, Tingting Li, Haitao Wang, Xiaosheng Zhang, Jinlong Zhang, Qiuyue Liu, Shuai Gao, Yuchang Yao, Jianyong Han, Suying Cao   +28 more
wiley   +1 more source

Changes in insulin-receptor structure associated with trypsin-induced activation of the receptor tyrosine kinase [PDF]

, 1991
Stella Clark, Glenn S. Eckardt, Kenneth Siddle, Len C. Harrison   +3 more
openalex   +1 more source

Do germline genetic variants affect the efficacy of epidermal growth factor receptor tyrosine kinase inhibitors? [PDF]

Transl Cancer Res
Masago K, Fujita S, Sasaki E, Horio Y.
europepmc   +1 more source

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source