Results 181 to 190 of about 625,224 (357)

Supplementary Figures 1-6, Table 1 from Toward the Prognostic Significance and Therapeutic Potential of HER3 Receptor Tyrosine Kinase in Human Colon Cancer

, 2023
Abdelhamid Beji, David Horst, Jutta Engel, Thomas Kirchner, Axel Ullrich   +4 more
openalex   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

KRASMutation Is an Important Predictor of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer [PDF]

, 2007
Erminia Massarelli, Marileila Varella‐Garcia, Ximing Tang, Ana C. Xavier, Natalie Ozburn, Diane D. Liu, B. Nebiyou Bekele, Roy S. Herbst, Ignacio I. Wistuba   +8 more
openalex   +1 more source

Supplementary Figure 4 from A Novel Inhibitor of c-Met and VEGF Receptor Tyrosine Kinases with a Broad Spectrum of <i>In Vivo</i> Antitumor Activities

, 2023
Yoshiko Awazu, Kazuhide Nakamura, Akio Mizutani, Yuichi Kakoi, Hidehisa Iwata, Seiji Yamasaki, Naoki Miyamoto, Shinichi Imamura, Hiroshi Miki, Akira Hori   +9 more
openalex   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Cholesterol promotes the formation of dimers and oligomers of the receptor tyrosine kinase ROR1. [PDF]

J Biol Chem
Ward A, Baeza-Ballesteros LJ, Schuck R, García-Murria MJ, Lamichhane R, Mingarro I, Barrera FN.   +6 more
europepmc   +1 more source

Characterization and Cloning of a 58/53-kDa Substrate of the Insulin Receptor Tyrosine Kinase

, 1996
Tammie C. Yeh, Wataru Ogawa, Anne Danielsen, Richard A. Roth   +3 more
openalex   +1 more source

Chemotactic Properties of Angiopoietin-1 and -2, Ligands for the Endothelial-specific Receptor Tyrosine Kinase Tie2 [PDF]

, 1998
Bernhard Witzenbichler, Peter C. Maisonpierre, Pamela F. Jones, George D. Yancopoulos, Jeffrey M. Isner   +4 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Autoregulation of the MET receptor tyrosine kinase by its intracellular juxtamembrane domain. [PDF]

Biochem J
Linossi EM, Espinoza CA, Estevam GO, Fraser JS, Jura N.   +4 more
europepmc   +1 more source