Results 11 to 20 of about 11,166,099 (105)

Context-responsiveness

, 2020
Context-responsiveness refers to the quality of a system, artefact or agent of dynamic feedback or adaptation in response to contextual conditions as they evolve in an interactional environment.
Amalia Sabiescu (3354257)
core   +7 more sources

Inflammatory mediators and angiogenic factors in choroidal neovascularization: pathogenetic interactions and therapeutic implications. [PDF]

Mediators Inflamm, 2010
Choroidal neovascularization (CNV) is a common and severe complication in heterogeneous diseases affecting the posterior segment of the eye, the most frequent being represented by age‐related macular degeneration. Although the term may suggest just a vascular pathological condition, CNV is more properly definable as an aberrant tissue invasion of ...
Campa C, Costagliola C, Incorvaia C, Sheridan C, Semeraro F, De Nadai K, Sebastiani A, Parmeggiani F.   +7 more
europepmc   +2 more sources

Distinct roles of immunoreceptor tyrosine‐based motifs in immunosuppressive indoleamine 2,3‐dioxygenase 1

Journal of Cellular and Molecular Medicine, Volume 21, Issue 1, Page 165-176, January 2017., 2017
Abstract The enzyme indoleamine 2,3‐dioxygenase 1 (IDO1) catalyses the initial, rate‐limiting step in tryptophan (Trp) degradation, resulting in tryptophan starvation and the production of immunoregulatory kynurenines. IDO1's catalytic function has long been considered as the one mechanism responsible for IDO1‐dependent immune suppression by dendritic ...
Elisa Albini, Verdiana Rosini, Marco Gargaro, Giada Mondanelli, Maria L. Belladonna, Maria Teresa Pallotta, Claudia Volpi, Francesca Fallarino, Antonio Macchiarulo, Cinzia Antognelli, Roberta Bianchi, Carmine Vacca, Paolo Puccetti, Ursula Grohmann, Ciriana Orabona   +14 more
wiley   +1 more source

Dynamic and volumetric variables reliably predict fluid responsiveness in a porcine model with pleural effusion [PDF]

, 2013
Background: The ability of stroke volume variation (SVV), pulse pressure variation (PPV) and global end-diastolic volume (GEDV) for prediction of fluid responsiveness in presence of pleural effusion is unknown.
Meybohm, Patrick, Matthias Gruenewald, Grünewald, Matthias Lars, Jan Schöttler, Katharina Heß, Steinfath, Markus, Heß, Katharina, Ole Broch, Jochen Renner, Schöttler, Jan, Patrick Meybohm, Bein, Berthold, Gruenewald, Matthias, Bein, Berthold Helmut, Berthold Bein, Renner, Jochen, Broch, Ole, Markus Steinfath   +17 more
core   +1 more source

Extraoral Taste Receptor Discovery: New Light on Ayurvedic Pharmacology

Evidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2017
More and more research studies are revealing unexpectedly important roles of taste for health and pathogenesis of various diseases. Only recently it has been shown that taste receptors have many extraoral locations (e.g., stomach, intestines, liver, pancreas, respiratory system, heart, brain, kidney, urinary bladder, pancreas, adipose tissue, testis ...
Marilena Gilca, Dorin Dragos, Marco Leonti   +2 more
wiley   +1 more source

Measurement of Serum Klotho in Systemic Sclerosis

Disease Markers, Volume 2017, Issue 1, 2017., 2017
Background. The aim of our study was to evaluate the serum concentration of klotho in a cohort of systemic sclerosis (SSc) patients compared to that of healthy controls and to correlate its levels with the degree and the kind of organ involvement. Methods.
Rossella Talotta, Sara Bongiovanni, Teresa Letizia, Federica Rigamonti, Maria Chiara Ditto, Fabiola Atzeni, Fausto Salaffi, Alberto Batticciotto, Maria Chiara Gerardi, Marco Antivalle, Tarcisio Vago, Maurizio Benucci, Piercarlo Sarzi-Puttini, Michele Malaguarnera   +13 more
wiley   +1 more source

Prognostic Significance of Circulating and Endothelial Progenitor Cell Markers in Type 2 Diabetic Foot

International Journal of Vascular Medicine, Volume 2014, Issue 1, 2014., 2014
Objective. We studied circulating precursor cells (CPC) in type 2 diabetes mellitus (T2DM) with neuropathic foot lesions with or without critical limb ischemia and relationships between endothelial precursor cells (EPC) and peripheral neuropathy. Methods and Subjects.
Maria Sambataro, Elena Seganfreddo, Fabio Canal, Anna Furlan, Laura del Pup, Monia Niero, Agostino Paccagnella, Filippo Gherlinzoni, Angelo Paolo dei Tos, Georgios Vourliotakis   +9 more
wiley   +1 more source

Estrogens as Antioxidant Modulators in Human Fertility

International Journal of Endocrinology, Volume 2013, Issue 1, 2013., 2013
Among treatments proposed for idiopathic male infertility, antiestrogens, like tamoxifen, play a possible role. On the other hand, oxidative stress is a mechanism well recognized for deleterious effects on spermatozoa function. After reviewing the literature on the effects of estrogens in modulation of antioxidant systems, in both sexes, and in ...
A. Mancini, S. Raimondo, M. Persano, C. Di Segni, M. Cammarano, G. Gadotti, A. Silvestrini, A. Pontecorvi, E. Meucci, Maria L. Dufau   +9 more
wiley   +1 more source

Stat3 Expression and Its Correlation with Proliferation and Apoptosis/Autophagy in Gliomas

Journal of Oncology, Volume 2008, Issue 1, 2008., 2008
Signal transducer and activator of transcription‐3 (Stat3) was studied along with several steps of the PI3/Akt pathway in a series of 64 gliomas that included both malignant and low‐grade tumors, using quantitative immunohistochemistry, Western blotting, and molecular biology techniques. The goal of the study was to investigate whether activated Stat3 (
Valentina Caldera, Marta Mellai, Laura Annovazzi, Guido Valente, Luciana Tessitore, Davide Schiffer, Massimo Aglietta   +6 more
wiley   +1 more source

Evaluating the responsiveness of the Warwick Edinburgh Mental Well-Being Scale (WEMWBS) : group and individual level analysis [PDF]

, 2012
Background: Mental well-being now features prominently in UK and international health policy. However, progress has been hampered by lack of valid measures that are responsive to change.
Maheswaran, H., John Powell, Weich Scott, Powell, J. (John), Powell, John, Maheswaran Hendramoorthy, Weich, S., Sarah Stewart-Brown, Hendramoorthy Maheswaran, Stewart-Brown Sarah, Stewart-Brown, Sarah, Powell John, Scott Weich, Powell, J., Stewart-Brown, S., Maheswaran, Hendramoorthy, Weich, Scott, Stewart-Brown, Sarah L.   +17 more
core   +1 more source