Results 71 to 80 of about 29,601 (261)
Analysis of the association between adiponectin, adiponectin receptor 1 and diabetic cardiomyopathy
Experimental and Therapeutic Medicine, 2014 The aim of this study was to explore the association between adiponectin (APN), APN receptors and insulin resistance (IR) using rats with type 2 diabetes mellitus (T2DM) as a model of diabetic cardiomyopathy (DC). Serum and cardiac APN levels were assessed using a double-antibody sandwich ELISA.
LI, JIEHUA, SU, SHIYUE, ZONG, XIAONA
openaire +3 more sources
Ronning After the Adiponectin Receptors [PDF]
Science, 2013 A small-molecule drug mimics the beneficial effects of adiponectin in cells and in animal models of diabetes and obesity.
William L. Holland, Philipp E. Scherer
openaire +1 more source
Arthritis &Rheumatology, EarlyView.Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
Adiponectin as novel key player in tumors of adrenal glands – what do we know? A review
Journal of Education, Health and Sport, 2019 Introduction: Adrenal incidentalomas without clinically apparent hormonal activities have becoming a huge socio-economic problem due to recent advances in radiological techniques.
Joanna Estera Szydełko +3 more
doaj +3 more sources
Exercise ameliorates the FGF21–adiponectin axis impairment in diet-induced obese mice
Endocrine Connections, 2019 Objective: The protective effects of exercise against glucose dysmetabolism have been generally reported. However, the mechanism by which exercise improves glucose homeostasis remains poorly understood.
Wenqi Yang +13 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić +7 more
wiley +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
MicroRNA-218 targets adiponectin receptor 2 to regulate adiponectin signaling
Molecular Medicine Reports, 2015 Adiponectin exerts an antidiabetic function through the adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2). The mechanism regulating the expression of adiponectin receptors remains to be elucidated. Bioinformatics analysis demonstrated that microRNA (miR)‑218 targets the 3' untranslated region (3'UTR) of the AdipoR2 mRNA.
Hechun, Du +6 more
openaire +3 more sources
Equine Veterinary Journal, EarlyView.Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé +6 more
wiley +1 more source