Results 81 to 90 of about 29,601 (261)

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

Periodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti, Jean E. Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

Adiponectin: Role in physiology and pathophysiology

International Journal of Preventive Medicine, 2020
Adiponectin, an adipokine secreted by adipocytes, is a well-known homeostatic factor for regulating glucose levels, lipid metabolism, and insulin sensitivity through its anti-inflammatory, anti-fibrotic, and antioxidant effects.
Thi Mong Diep Nguyen
doaj   +1 more source

Role of adiponectin and its receptors in cancer.

Cancer biology & medicine, 2012
Adiponectin (APN), a novel hormone/cytokine derived from adipocyte tissue, is involved in various physiological functions. Genetics, nutrition, and adiposity are factors contributing to circulating plasma concentrations of APN. Clinical correlation studies have shown that lower levels of serum APN are associated with increased malignancy of various ...
Obeid, Stephanie, Hebbard, Lionel
openaire   +4 more sources

Prevalence of insulin dysregulation in a sport horse population as determined by traditional and stall‐side testing

Equine Veterinary Journal, EarlyView.
Abstract Background The prevalence of insulin dysregulation (ID) has not been investigated in sport horses. Stall‐side insulin assays offer convenience but need further validation. Objectives To determine the prevalence of and risk factors for ID in a sport horse population using an oral sugar test (OST) and assess agreement between stall‐side and ...
Kimberly L. Hallowell, Caitlyn R. Horne, Cary S. Miller, Sara R. Tufts, Katarzyna Dembek, Kim R. Love, Andrew W. van Eps, Lauren V. Schnabel   +7 more
wiley   +1 more source

AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis

Nature Communications, 2020
Nonalcoholic steatohepatitis (NASH) and associated liver fibrosis have limited therapy options. Here the authors report a novel adiponectin-based dual agonist for adiponectin receptors 1 and 2 with a longer half-life, and show that it ameliorates NASH ...
Hongjiao Xu, Qian Zhao, Nazi Song, Zhibin Yan, Runfeng Lin, Shuohan Wu, Lili Jiang, Sihua Hong, Junqiu Xie, Huihao Zhou, Rui Wang, Xianxing Jiang   +11 more
doaj   +1 more source

The effect of adiponectin and adiponectin receptors in bone

, 2019
The adipokine adiponectin exerts many complex endocrine and paracrine biological effects, particularly regulation of insulin sensitivity and glucose homeostasis. Despite bone marrow cells producing the majority of adiponectin, its role in bone accrual and homeostasis remains controversial, with contradictory reports from human and mouse studies ...
openaire   +1 more source

Effects of Short-Term Exercise on Adiponectin and Adiponectin Receptor Levels in Rats

Journal of Atherosclerosis and Thrombosis, 2007
Adiponectin reportedly reduces insulin resistance. Exercise has also been shown to lessen insulin resistance, although it is not well known whether exercise increases levels of adiponectin and/or its receptors nor whether it effects are dependent on exercise intensity and/or period. We previously reported that blood adiponectin levels increased by 150%
Zeng, Qin, Fu, Ling, Takekoshi, Kazuhiro, Kawakami, Yasushi, Isobe, Kazumasa   +4 more
openaire   +3 more sources

Proso Millet (Panicum miliaceum): Nutritional Composition, Functional Attributes, and Health Implications

Future Postharvest and Food, EarlyView.
A nutrient‐dense grain, proso millet is well‐known for its high protein content and vital amino acids. It is high in fiber, vitamins, and minerals and has many health advantages, including promoting heart health, enhancing digestion, and helping with weight management.
Sangeeta Yadav, Pratiksha Singh, Mazia Ahmed, Pinki Saini   +3 more
wiley   +1 more source

Pharmacological Blocking of Adiponectin Receptors Induces Alzheimer’s Disease-like Neuropathology and Impairs Hippocampal Function

Biomedicines
Background/Objectives: Previous studies have shown that adiponectin deficiency or blocking adiponectin receptors (AdipoRs) in the brain can lead to an Alzheimer’s disease (AD)-like neuropathology.
Hui-Hui Guo, Hai-Ning Ou, Jia-Sui Yu, Suk-Yu Yau, Hector Wing-Hong Tsang   +4 more
doaj   +1 more source

Lack of adiponectin and adiponectin receptor 1 contributes to benign prostatic hyperplasia

Oncotarget, 2017
The incidence of benign prostatic hyperplasia increases among obese individuals, but few studies have fully explained the underlying mechanisms. Adiponectin has drawn much attention in recent years due to its protective role in obesity-related diseases.
Fu, Shi, Xu, Huan, Gu, Meng, Liu, Chong, Wan, Xiang, Chen, Yanbo, Chen, Qi, Zhou, Juan, Wang, Zhong   +8 more
openaire   +3 more sources