Results 241 to 250 of about 141,931 (309)

Characterization of alpha-1 adrenergic receptors linked to [3H]inositol metabolism in rat cerebral cortex.

Journal of Pharmacology and Experimental Therapeutics, 1984
The properties of alpha-1 adrenergic receptors in rat cerebral cortex were examined by measuring increases in [3H]inositol metabolism in brain slices.
K. Minneman, R. D. Johnson
semanticscholar   +1 more source

Turnover in vivo of alpha 1-adrenergic receptors in rat submaxillary glands.

Molecular Pharmacology, 1983
In submaxillary glands, vas deferens, and cerebral cortex, [3H]prazosin labeled one homogeneous population of alpha 1-adrenergic receptors having a KD of 0.1 nM.
F. Sladeczek, J. Bockaert
semanticscholar   +1 more source

The alpha-1 Adrenergic Receptors

1987
Section 1: Historical Perspectives.- 1 alpha-1 Adrenergic Receptors: A Historical Perspective.- 1. Introduction.- 2. Adrenotropic Receptors.- 3. Receptor Blockers.- 4. Recent Developments.- 5. Conclusion.- References.- Section 2: Characterization of the Receptor and Its Binding Site.- 2 Biochemistry and Pharmacology of the alpha-1 Adrenergic Receptor.-
openaire   +1 more source

Subtypes of alpha-1 and alpha-2 adrenergic receptors

European Neuropsychopharmacology, 1992
The adrenergic receptors are members of the superfamily of G protein-coupled receptors. There are three major types of adrenergic receptors: alpha 1, alpha 2, and beta. Each of these three major types can be divided into three subtypes. Within the alpha 1-adrenergic receptors, alpha 1A and alpha 1B subtypes have been defined pharmacologically on the ...
openaire   +2 more sources

Prostaglandin synthesis and renal vasoconstriction elicited by adrenergic stimuli are linked to activation of alpha-1 adrenergic receptors in the isolated rat kidney.

Journal of Pharmacology and Experimental Therapeutics, 1985
The authors have investigated the effect of norepinephrine (NE) and selective alpha-1, alpha-2 and beta adrenergic receptor agonists and antagonists on prostaglandin (PG) output and vascular tone to determine the type of adrenergic receptor involved in ...
C. L. Cooper, K. Malik
semanticscholar   +1 more source

Regulation of alpha-1 Adrenergic Receptors

1987
Catecholamines modulate a wide variety of important physiological processes, alpha-1 Adrenergic receptors play a major role in transducing many of the actions of catecholamines. A particularly prominent action of alpha-1 adrenergic receptors is the promotion of vasoconstriction in a range of vascular beds.
openaire   +1 more source

Phosphoinositides and alpha-1 Adrenergic Receptors

1987
In 1953, Hokin and Hokin demonstrated that muscarinic cholinergic stimulation of pancreatic fragments increased the turnover of cellular phosphatidylinositol (PI), as measured by an increased incorporation of radioactive phosphorus from inorganic phosphate in the incubation medium (Hokin and Hokin, 1953, 1954).
openaire   +1 more source

alpha-1 Adrenergic Receptors in the Central Nervous System

1987
The cell bodies of norepinephrine-containing central neurons are localized in nuclei in the reticular formation of the lower brain stem. These nuclei are labeled A1-A7 (Dahlstrom and Fuxe, 1964), and can be divided into two groups: (1) the lateral tegmental system, innervating the hypothalamus, brainstem, spinal cord, and basal ganglia, and (2) the ...
E. Szabadi, C. M. Bradshaw
openaire   +1 more source

Prostaglandin synthesis elicited by adrenergic stimuli in rabbit aorta is mediated via alpha-1 and alpha-2 adrenergic receptors.

Journal of Pharmacology and Experimental Therapeutics, 1990
The purpose of this study was to characterize the type of adrenergic receptor(s) involved in both prostaglandin (PG) synthesis and the contractile response elicited by adrenergic receptor agonists in the rabbit aorta.
C. Nebigil, Kafait U. Malik
semanticscholar   +1 more source

Appearance of alpha 1-adrenergic receptors in soleus muscles from SHR

American Journal of Physiology-Cell Physiology, 1992
The depressed functional capabilities of spontaneously hypertensive rat (SHR) muscles, reported previously (Exp. Neurol. 95: 249-264, 1987), may reflect a decrease in muscle responsiveness to catecholamines occurring as a consequence of exposure to the elevated level of plasma catecholamines in SHR.
J G, Pickar, S D, Gray, R C, Carlsen
openaire   +2 more sources