Results 241 to 250 of about 1,410,707 (305)

Alpha-Adrenergic Receptor Subtypes

New England Journal of Medicine, 1980
CATECHOLAMINES modulate a host of diverse responses in man. These responses are initiated by the interaction of catecholamines with discrete sites located on the plasma membrane of cells. Adrenergic receptors, like other hormone receptors, are responsible for the selective recognition and binding of specific molecular structures, in this case ...
B B, Hoffman, R J, Lefkowitz
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Alpha-adrenergic receptors on human platelets

Life Sciences, 1977
Abstract [3H] dihydroergocyrptine, an α-adrenergic antagonist, binds specifically to sites on human platelet membranes. Prostaglandin E1 (PGE1) stimulates the production of cyclic AMP (cAMP) in human platelets. Alpha-adrenergic agonists, 1-epinephrine and 1-norepinephrine, and antagonists, phentolamine, phenoxybenzamine, and dihydroergocyrptine ...
M S, Kafka, J F, Tallman, C C, Smith, J L, Costa   +3 more
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Alpha-Adrenergic Receptors In Rabbit Eyes

Journal of Ocular Pharmacology and Therapeutics, 1985
The IOP and pupil response to alpha-adrenergic agonists and blockers was studied in albino rabbits. Topical ocular application of solutions of methoxamine (alpha 1) and oxymetazoline (alpha 2) caused dose-related early rises in IOP which were inhibited by pretreatment with prazosin, an alpha 1-blocker, or with yohimbine, an alpha 2-blocker.
D L, Murray, I H, Leopold
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Structure and Function of Alpha-Adrenergic Receptors

The American Journal of Medicine, 1989
Alpha 1- and alpha 2-adrenergic receptors are the initial recognition sites on a wide variety of catecholamine-responsive target cells. This article addresses several major questions related to subtypes, structure, signal transduction mechanisms, and regulation of alpha 1- and alpha 2-adrenergic receptors.
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Central alpha adrenergic receptors in thermoregulation

Neuropharmacology, 1972
Abstract Alpha and beta adrenergic receptor blocking agents were injected into the cerebral ventricles of unanesthetized cats and their effects on subsequent responses to intraventricular norepinephrine were determined. The alpha receptor blocking agent phentolamine (100 μg) antagonized the hypothermie and emetic responses to 100 μg norepinephrine ...
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Subtypes of alpha-1 and alpha-2 adrenergic receptors

European Neuropsychopharmacology, 1992
The adrenergic receptors are members of the superfamily of G protein-coupled receptors. There are three major types of adrenergic receptors: alpha 1, alpha 2, and beta. Each of these three major types can be divided into three subtypes. Within the alpha 1-adrenergic receptors, alpha 1A and alpha 1B subtypes have been defined pharmacologically on the ...
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alpha-2 Adrenergic Receptors

1988
The actions of epinephrine, an adrenal hormone and central neurotransmitter, and norepinephrine, a peripheral sympathetic and central neurotransmitter, are mediated through alpha-1, alpha-2, and beta-adrenergic receptors. In addition, a variety of drugs also produce their effects by interacting with these receptors. alpha-2 Adrenergic agonists, such as
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alpha1-Adrenergic Receptor Subtypes

Annual Review of Pharmacology and Toxicology, 1994
Investigators have not yet reached a consensus on the number and signaling mechanisms of alpha 1-adrenergic receptor (AR) subtypes. Two native subtypes (alpha 1A and alpha 1B) can be distinguished pharmacologically, and three subtypes (alpha 1B, alpha 1C, and alpha 1D) have been cloned.
K P, Minneman, T A, Esbenshade
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ALPHA-ADRENERGIC RECEPTORS IN HUMAN OMENTUM?

The Lancet, 1969
J, Ostman, S, Efendić
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Alpha-Adrenergic Receptors in the Human Lung

Psychosomatic Medicine, 1971
R F, Anthracite, L, Vachon, P H, Knapp
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