Results 31 to 40 of about 248,286 (331)

Dynamics of prostate protectors assortment in the state formulary of medicines of 1-9 issues

open access: yesФармацевтичний журнал, 2018
Prostatitis is one of the most frequent urology diseases of men of reproductive age. Recommendations for rational pharmacotherapy prostatitis are included into the State Formulary of Medicines, which is reviewed and updated annually. Thus, the aim of our
І. V. Gadyak, B. P. Hromovyk
doaj   +1 more source

Postsynaptic alpha-adrenergic receptors potentiate the beta-adrenergic stimulation of pineal serotonin N-acetyltransferase.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1983
The role played by postsynaptic alpha-adrenergic receptors in the stimulation of pineal N-acetyltransferase (EC 2.3.1.5) and [3H]melatonin production was investigated in the rat.
D. Klein, D. Sugden, J. Weller
semanticscholar   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

open access: yesHepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro   +14 more
wiley   +1 more source

Reciprocal hunger-regulating circuits involving alpha- and beta-adrenergic receptors located, respectively, in the ventromedial and lateral hypothalamus.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1970
The injection of adrenergic and adrenolytic drugs directly into the brain through permanently implanted cannulas has yielded results showing that food consumption in the rat is regulated by a hypothalamic alpha-adrenergic "hunger" system.
S. Leibowitz
semanticscholar   +1 more source

Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]

open access: yes, 2004
Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C.   +2 more
core   +1 more source

Increased alpha-adrenergic receptors in ischemic cat myocardium. A potential mediator of electrophysiological derangements.

open access: yesJournal of Clinical Investigation, 1981
We have recently demonstrated enhanced alpha-adrenergic responsiveness assessed electrophysiologically in ischemic and reperfused myocardium. This study was performed to determine whether ischemia alters alpha 1-adrenergic receptor number (Bmax) of ...
P. Corr   +3 more
semanticscholar   +1 more source

Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]

open access: yes, 2017
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M.   +3 more
core   +1 more source

Assessment of melatonin-alpha adrenergic receptor complexes by molecular docking analysis

open access: yesBrazilian Journal of Biology, 2022
The pineal melatonin (N-acetyl-5-methoxytryptamine) is a molecule associated in a way or another with probably all physiological systems, aiming to fulfil its functional integrative roles in central nervous system activity, sleep and wakefulness cycles ...
V. G. Borges, J. E. Gabriel
doaj   +1 more source

Differences in the signaling pathways of α1A- and α1B-adrenoceptors are related to different endosomal targeting [PDF]

open access: yes, 2013
Aims: To compare the constitutive and agonist-dependent endosomal trafficking of α1A- and α1B-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype.
A Hirasawa   +54 more
core   +6 more sources

Floppy iris syndrome associated with specific medication intake: A narrative review

open access: yesBiomedical Papers, 2023
Intraoperative floppy iris syndrome (IFIS) is a cataract surgery complication that remains a challenge for eye surgeons. It is caused by the antagonism of alfa-1-adrenergic receptors within the dilator muscle of the iris, thus preventing the iris from ...
Miroslava Maluskova   +4 more
doaj   +1 more source

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