Results 51 to 60 of about 1,410,707 (305)

Two cases of priapism associated with Quetiapine

open access: yesPsychiatry and Clinical Psychopharmacology, 2018
Priapism is a painful, prolonged erection that occurs without any sexual stimulation. It is an emergency that may lead impotence, urinary retention, and gangrene as long-term devastating consequences.
Özge Şahmelikoğlu Onur   +3 more
doaj   +1 more source

Alpha adrenergic receptors

open access: yes, 2000
This project examined the transcriptional regulation of the 2A adrenergic receptors in a central adrenergic cell line (CATH.a). The study suggests that cAMP induces the transcription of 2A gene in these cells. It is also consistent with the fact that the
Felekkis, Kyriacos Nicos
core   +3 more sources

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

open access: yesAdvanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang   +12 more
wiley   +1 more source

Alpha adrenergic receptors in renal pelvis and calyces: can rat models be used?

open access: yesInternational Brazilian Journal of Urology, 2014
We aimed, in this study, to determine the distribution of α-1 AR subtypes in rat and human pelvis and calyces, and to evaluate, by comparing these two species, the possibility of rats to be used as models for humans.
Osman Raif Karabacakb   +6 more
doaj   +1 more source

Changes in expression of alpha-1, 2 and β-2 adenoidal receptor gene in cumulus cells of infertile women with polycystic ovary syndrome (IVF candidate) and effect of clonidine on it [PDF]

open access: yesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019
Introduction: Ovarian function should control follicle development, steroidogenesis, and ovulation processes by ovarian external and internal hormonal signals.
Farideh Zafari Zangeneh   +3 more
doaj   +1 more source

Cardiac adrenergic control and atrial fibrillation [PDF]

open access: yes, 2010
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it causes substantial mortality. The autonomic nervous system, and particularly the adrenergic/cholinergic balance, has a profound influence on the occurrence of AF ...
Workman, A.J.
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Alpha blockers: A relook at phenoxybenzamine

open access: yesJournal of the Practice of Cardiovascular Sciences, 2017
Phenoxybenzamine (PBZ) is an alpha adrenergic antagonist, used for the management of hypertension. PBZ acts by blocking alpha-adrenergic receptors, leading to vasodilatation and low systemic vascular resistance. This helps in control of blood pressure in
Sambhunath Das   +3 more
doaj   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

open access: yesAdvanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia   +13 more
wiley   +1 more source

Clonidine treatment delays postnatal motor development and blocks short-term memory in young mice. [PDF]

open access: yesPLoS ONE, 2014
During the development of the nervous system, the perinatal period is particularly sensitive as neuronal connections are still forming in the brain of the neonate.
Cristina Calvino-Núñez   +1 more
doaj   +1 more source

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