Results 31 to 40 of about 39,458 (264)
Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Influence of on Alpha-Adrenergic Receptor of Benign Prostatic Hyperplasia [PDF]
International Neurourology Journal, 2014 Purpose Benign prostatic hyperplasia (BPH) is the most common prostate problem in older men. The present study aimed to investigate the inhibitory effect of Panax ginseng C.A. Meyer ( P. ginseng) on a rat model of testosterone-induced BPH.
Su Kang Kim +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Modulation of Alpha 1 Adrenergic Receptors on Urinary Bladder in Rat Spinal Cord Injury Model [PDF]
International Neurourology Journal, 2012 Purpose Whereas many studies have focused on the vesical changes of the α1 adrenergic receptor (AR) subtypes in partial outlet obstruction, few studies have addressed the modulation of the α1 AR subtypes after spinal cord injury (SCI).
Gilho Lee +3 more
doaj +1 more source
Bioprinting High‐Cell‐Density Cardiac Tissue Constructs With Sustained Contractile Function
Advanced Healthcare Materials, EarlyView.Contractile cardiomyocytes in 3D culture provide insights into the behavior of the heart. Combining a 3D bioprinting approach with a multi‐electrode array allows the development of the 3D culture to be monitored over time, and matured cultures allow the effect of drugs on cardiac function to be modelled, replicating effects seen in clinical application.
Priscila Melo +8 more
wiley +1 more source
Two cases of priapism associated with Quetiapine
Psychiatry and Clinical Psychopharmacology, 2018 Priapism is a painful, prolonged erection that occurs without any sexual stimulation. It is an emergency that may lead impotence, urinary retention, and gangrene as long-term devastating consequences.
Özge Şahmelikoğlu Onur +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi +10 more
wiley +1 more source
Alpha adrenergic receptors in renal pelvis and calyces: can rat models be used?
International Brazilian Journal of Urology, 2014 We aimed, in this study, to determine the distribution of α-1 AR subtypes in rat and human pelvis and calyces, and to evaluate, by comparing these two species, the possibility of rats to be used as models for humans.
Osman Raif Karabacakb +6 more
doaj +1 more source
Changes in expression of alpha-1, 2 and β-2 adenoidal receptor gene in cumulus cells of infertile women with polycystic ovary syndrome (IVF candidate) and effect of clonidine on it [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019 Introduction: Ovarian function should control follicle development, steroidogenesis, and ovulation processes by ovarian external and internal hormonal signals.
Farideh Zafari Zangeneh +3 more
doaj +1 more source
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
Advanced Science, EarlyView.We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source