Results 261 to 270 of about 295,622 (354)

Advancements in Beta-Adrenergic Therapy and Novel Personalised Approach for Portal Hypertension: A Narrative Review. [PDF]

Life (Basel)
Avram RI, Minea HO, Huiban L, Damian IR, Muset MC, Juncu S, Muzica CM, Zenovia S, Singeap AM, Girleanu I, Stanciu C, Trifan A.   +11 more
europepmc   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

The neuro-immune axis in cancer: mechanisms of innervation-driven tumor progression and therapeutic opportunities. [PDF]

Front Immunol
Zhang L, Zhu D, Wang J, Guo J, Jiang M, Qi X, Zhang Z, Zheng Z.   +7 more
europepmc   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Poorer Clinical Outcomes and Longer Hospitalization with Beta Blocker Discontinuation in Acute Decompensated Heart Failure Wet and Warm: A Retrospective Study. [PDF]

Hosp Pharm
Alsagaff MY, Afrilla D, Jannati D, Nilamsari WP, Maghfirah I, Jaya HP.   +5 more
europepmc   +1 more source

Beta adrenergic signaling as a therapeutic target for autoimmunity. [PDF]

J Neuroimmunol
Lauten TH, Reed EC, Natour T, Pitts LJ, Jojo CN, Griffin BL, Case AJ.   +6 more
europepmc   +1 more source

Prognostic Impact of Concomitant Beta-Blocker Use on Survival in EGFR-Mutant Metastatic Non-Small Cell Lung Cancer Patients Treated with Erlotinib. [PDF]

Medicina (Kaunas)
Yıldız O, Aykut T, Kaya BE, Genç Ö, Gürbüz AF, Saçkan F, Eryılmaz MK, Koçak MZ, Araz M, Artaç M.   +9 more
europepmc   +1 more source

Bile Canalicular Bitter Taste Receptors Inhibit β-Adrenergic Receptor-Induced Lipolysis in Steatotic Hepatocytes. [PDF]

Int J Mol Sci
Xue YB, Gong SM, Peng YY, Yu D, Zhou R, Huang L.   +5 more
europepmc   +1 more source

Understanding CPVT pathogenic mechanisms based on mutation location within RyR2: towards personalized medicine?

The Journal of Physiology, EarlyView.
Jean‐Pierre Benitah, Esther Zorio, Ana María Gómez   +2 more
wiley   +1 more source

Suppression of pre-B cell colony formation by catecholamine oxidation. [PDF]

J Immunol
Roberts NT, Daneshmandi S, Choi JE, Repasky EA.   +3 more
europepmc   +1 more source