Results 121 to 130 of about 86,830 (247)

Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals

open access: yesIntegrative Zoology, EarlyView.
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley   +1 more source

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi   +4 more
wiley   +1 more source

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

open access: yesAllergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco   +38 more
wiley   +1 more source

The role of α<sub>2</sub>-adrenergic mechanisms in sympathetic baroreflex control of human blood pressure. [PDF]

open access: yesAm J Physiol Heart Circ Physiol
Spafford JE   +11 more
europepmc   +1 more source

Risk of priapism after dynamic penile Doppler ultrasound: Single‐centre experience on a large cohort of patients

open access: yesAndrology, EarlyView.
Abstract Objectives To evaluate the risk of priapism in patients undergoing Dynamic—Penile duplex ultrasound (D‐PDU) who were referred to our Unit between January 2022 and December 2023. Patients and methods We enrolled 292 patients, of whom 268 underwent Dynamic—Penile duplex ultrasound for erectile dysfunction and 24 for Peyronie's disease.
Giuseppe Grande   +6 more
wiley   +1 more source

Dorsal Genital Nerve Stimulation as an Adjunctive Therapy to Control Neurogenic Detrusor Overactivity After Spinal Cord Injury

open access: yesArtificial Organs, EarlyView.
People with spinal cord injury (SCI) experience bladder overactivity, which can cause incontinence. Dorsal genital nerve stimulation (DGNS) can suppress overactivity, providing a longer duration to reach a toilet. People with SCI trialed home‐based DGNS for 8 weeks. DGNS was effective in the laboratory, and participants found home‐based DGNS acceptable.
Sean Doherty   +4 more
wiley   +1 more source

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