Results 121 to 130 of about 103,939 (309)
ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher +12 more
wiley +1 more source
Immuno-oncological effects of the α2-adrenoceptor agonist dexmedetomidine
OncoImmunologyThe α2-adrenergic receptor agonist dexmedetomidine (DEX) exerts context-dependent antitumor effects, with its efficacy influenced by dose, immune cell involvement and combination with immune checkpoint inhibitors.
Lucillia Bezu +2 more
doaj +1 more source
Molecular analysis of the histamine H3-receptor
, 2010 The histamine H3 receptor (H3R) is a biogenic amine receptor that belongs to family I of G protein-coupled receptors (GPCRs). During the past two decades, the H3R has gained much interest in academia and industry.
Schnell, David
core +1 more source
Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial
ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad +9 more
wiley +1 more source
Status epilepticus: Updates on mechanisms and treatments
Epilepsia Open, EarlyView.Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
␣ 1 -Adrenergic Receptors Regulate Neurogenesis and Gliogenesis
, 2020 The understanding of the function of ␣ 1 -adrenergic receptors in the brain has been limited due to a lack of specific ligands and antibodies. We circumvented this problem by using transgenic mice engineered to overexpress either wild-type receptor ...
R J G +9 more
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Characterisation and regulation of muscarinic and adrenergic receptors Subtitle: The effect of stress on muscarinic and adrenergic receptors in the lung and in the heart [PDF]
, 2011 The aim of this thesis was to clarify the influence of the stress on the adrenergic and muscarinic receptors in the heart and in the lungs. Research was perform on rat hearts and lungs and on the hearts and lungs of the CRH KO mice.
Nováková, Martina
core
Amiloride interacts with renal alpha- and beta-adrenergic receptors
, 1987 We have used radioligand binding techniques to assess whether amiloride and certain analogues of amiloride (ethylisopropyl amiloride and benzamil) can bind to adrenergic receptors in the kidney. We found that amiloride could compete for [3H]rauwolscine (
M. D. Mullen, P. A. Insel, M. J. Howard
core +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska +4 more
wiley +1 more source
Autoradiographic quantification of adrenergic receptors in rat kidney
, 1990 Autoradiographic quantification of adrenergic receptors in rat kidney. The adrenergic nervous system is active in kidney function, and the kidney has large numbers of adrenergic receptor subtypes.
Calianos, Theodore, Muntz, Kathryn H.
core +1 more source