Results 171 to 180 of about 172,419 (282)

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

Artificial Organs, EarlyView.
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht, Baran Ogurlu, Silke S. M. Wolfswinkel, Henri G. D. Leuvenink, Cyril Moers   +4 more
wiley   +1 more source

Acute Exercise-Induced Epinephrine Elevation Promotes Post-Learning Memory Consolidation: A Narrative Review of Mechanisms and Implementation Strategies. [PDF]

Life (Basel)
Zhang Y, Lin X, Li G, Wang S.
europepmc   +1 more source

Population‐Based Cohort Study for Development of National Retinopathy of Prematurity Screening Criteria

Acta Paediatrica, EarlyView.
ABSTRACT Aim Screening criteria for retinopathy of prematurity (ROP) vary among countries. Early detection of ROP and minimising the burden of screening are important. Methods We analysed data from very preterm infants born in Switzerland between 2006 and 2022.
R. Gerull, C. Sanchez, A. Atkinson, M. Schuler‐Barazzoni, M. Adams, F. Barcos Munoz, C. Gerth‐Kahlert, S. M. Schulzke, on behalf of the Swiss Neonatal Network, Ph. Meyer, L. Eisenhut, M. Bryant, A. Kidszun, T. Riedel, M. Gebauer, B. Rogdo, B. Wagner, R. E. Pfister, J.‐F. Tolsa, J. Schneider, M. Stocker, P. Gessler, B. Laubscher, J. Llor, A. Malzacher, A. Birkenmaier, L. Hegi, V. Bernet, M. Tomaske, D. Bassler, V. Cannizzaro, C. Hagmann   +31 more
wiley   +1 more source

Central injection of epidermal growth factor (EGF) induces hypophagia via D₁ dopaminergic and β₂ adrenergic receptors in broiler chickens. [PDF]

Poult Sci
Jafari-Ardakan Z, Zendehdel M, Mahdavi K.   +2 more
europepmc   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Part 1 - imidazolines and the changing face of nasal decongestants. [PDF]

Front Pharmacol
Stinson RJ, Sadofsky LR.
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Β3-Adrenergic Receptors and Prematurity-Related Diseases: A Systematic Review. [PDF]

Children (Basel)
Fazi C, Dani C.
europepmc   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Chronic β-Blockade and Systemic Homeostasis: Molecular Integration of Cardiorenal and Immune Pathways, a Narrative Review. [PDF]

Biomolecules
Park J, Hamanaka A, Park I, Abdelhady HG.   +3 more
europepmc   +1 more source