Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams +6 more
wiley +1 more source
Antinociceptive Effect of Cinnamaldehyde in Male Mice: Investigation of the Mechanisms of Action Through In Silico and In Vivo Approaches. [PDF]
Rêgo RIA +10 more
europepmc +1 more source
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer +4 more
wiley +1 more source
Sympathetic nerve aggravates autoimmune skin disease via NE-adrenergic receptor axis: Neuroimmune cross-talk insights from vitiligo. [PDF]
Huang L +10 more
europepmc +1 more source
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou +6 more
wiley +1 more source
Single-cell transcriptomics reveals ADRB1 as a key immune checkpoint regulating T cell exhaustion in lung cancer and its prognostic value in lung cancer. [PDF]
Cao Z +9 more
europepmc +1 more source
Management of Paediatric Acute Asthma in a Metropolitan Emergency Department: A Retrospective Audit
ABSTRACT Aim To evaluate adherence to the Sydney Children's Hospital Network (SCHN) Asthma‐Acute Management Practice Guideline in the management of paediatric patients presenting to a metropolitan emergency department (ED). Methods A cross‐sectional retrospective audit of 153 paediatric ED presentations with acute asthma between March 2023 and February
Yasmine Toufaili, Nounu Sarukkali
wiley +1 more source
Single-dose Tamsulosin Induces Reversible Azoospermia and Ejaculatory Dysfunction Suggesting Potential for on-demand Male Contraception. [PDF]
Lopes LS +9 more
europepmc +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source
Synephrine potentiates lidocaine-induced cutaneous analgesia via α-adrenergic receptors in male rats. [PDF]
Chou AK +5 more
europepmc +1 more source

