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GRKs phosphorylate GPCR C-terminal peptides in a hierarchical manner
Löbbert A +5 more
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Adrenergic Receptors in the Heart [PDF]
Annual Review of Physiology, 1982 Introduction Catecholamines, acting through alphaand beta-adrenergic receptors, modulate a variety of physiological responses in the heart. Most impor tantly catecholamines increase the rate and force of cardiac contraction. These actions occur mainly as a consequence of the binding of the endoge nous substances norepinephrine and epinephrine to ...
Brian B. Hoffman, Robert J. Lefkowitz
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The hepatic adrenergic receptors
Molecular and Cellular Biochemistry, 1980The presence of both alpha- and beta-adrenergic receptors in liver designated the hepatic plasma membrane as a useful tool for the elucidation of the mechanisms by which the hormonal signal is transferred through the membrane via a coupling system to an amplifying entity.
Paul-Henry Schmelck, Jacques Hanoune
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Annual Review of Medicine, 1984
Recently developed pharmacological and biochemical techniques have brought new insights about the structure, function, and regulation of beta-adrenergic receptors. This chapter focuses on the cardiac beta-adrenergic receptor and the possible clinical and physiological implications of this new information.
Gary L. Stiles, Robert J. Lefkowitz
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Recently developed pharmacological and biochemical techniques have brought new insights about the structure, function, and regulation of beta-adrenergic receptors. This chapter focuses on the cardiac beta-adrenergic receptor and the possible clinical and physiological implications of this new information.
Gary L. Stiles, Robert J. Lefkowitz
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1984
Adrenergic receptors are discrete recognition sites located on the plasma membrane of cells. Their primary function is to recognize and to bind epinephrine and related molecules, which can initiate several biochemical processes resulting in a physiological response.
Anna Borsodi, Maria Wollemann
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Adrenergic receptors are discrete recognition sites located on the plasma membrane of cells. Their primary function is to recognize and to bind epinephrine and related molecules, which can initiate several biochemical processes resulting in a physiological response.
Anna Borsodi, Maria Wollemann
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ChemInform Abstract: ADRENERGIC RECEPTOR AGONISTS
Chemischer Informationsdienst, 1980AbstractDie Hydroxybenzaldehyde (I) setzen sich mit Chloraceton (II) zu den Benzofuranen (III) um.
J. L. G. Nilsson +2 more
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Biotechnology of β-adrenergic receptors [PDF]
Molecular Neurobiology, 1990 This article discusses the structural and functional features of a new family of membrane receptors including alpha-adrenergic and beta-adrenergic receptors for catecholamines, muscarinic receptors for acetylcholine, and receptors for histamine, dopamine, serotonin, and neuropeptides such as angiotensin.
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Molecular biology of adrenergic receptors
Journal of Hypertension, 1992G protein-coupled receptors respond to many neuro- and autocrine transmitters. Among these receptors, adrenergic receptors are particularly important in the regulation of cardiovascular function. The primary physiological agonists for these receptors are epinephrine and norepinephrine, which have been used to differentiate α- and s-receptor families [1]
Ruth H. Strasser +2 more
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Regulation of Adrenergic Receptors [PDF]
, 1981 Transmission of intercellular messages by the adrenergic mediators, epinephrine and norepinephrine, is a ubiquitous phenomenon in vertebrates which continues to invoke investigative effort after many years of research. It has become apparent that both the release and biological actions of these mediators are modulated very specifically by ...
Robert J. Lefkowitz, Albert O. Davies
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Structure of β-Adrenergic Receptors
2013β-Adrenergic receptors (βARs) control key physiological functions by transducing signals encoded in catecholamine hormones and neurotransmitters to activate intracellular signaling pathways. As members of the large family of G protein-coupled receptors (GPCRs), βARs have a seven-transmembrane helix topology and signal via G protein- and arrestin ...
Brueckner Florian +5 more
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