Neuroimmunomodulation of AMPA Receptors Through Combination of Medium-Chain Triglycerides and Perampanel to Treat Status Epilepticus in Anti-NMDA Receptor Encephalitis. [PDF]
Stadler LM +7 more
europepmc +1 more source
Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz +4 more
wiley +1 more source
Increase of the AMPA-evoked response of pyramidal neurons in the rat medial prefrontal cortex following acute administration of ketamine and S-ketamine, but not R-ketamine. [PDF]
El Mansari M, Okamoto N, Blier P.
europepmc +1 more source
Creutzfeldt‐Jakob‐Like Presentation in Anti‐AMPAR Encephalitis
Annals of Neurology, Volume 99, Issue 6, Page 1466-1467, June 2026.
Kate Durbano +3 more
wiley +1 more source
Editorial: Cross-talk of synaptic proteins in neurological diseases. [PDF]
Annamneedi A +3 more
europepmc +1 more source
Intermediate filaments link glutamate–aspartate transporter deficiency to cochlear synaptopathy
In a healthy ear, GLAST transporters in supporting cells clear excess glutamate to protect auditory connections. When GLAST is missing, glutamate accumulates and leads to the destruction of structural scaffolding within the postsynaptic nerve endings. This internal collapse causes a loss of synapses that are essential for hearing, ultimately resulting ...
Paul Emmerich Krumpoeck +1 more
wiley +1 more source
Septins in the Middle—Makers and Breakers of Membrane Contact Sites
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley +1 more source
Calcium signaling and postsynaptic density dynamics: the roles of calmodulin in synaptic protein regulation. [PDF]
Shah KD, Zhang Y.
europepmc +1 more source
Brainstem Astrocytes Regulate Estrus‐Dependent Oscillations in Food Intake
DVC astrocytes regulate food intake and caloric balance via modulation of NMDA receptor‐mediated glutamatergic signaling to brainstem DMV motoneurons. In female rats, GFAP‐IR intensity and astrocyte morphological complexity increased during periods of high estrogen levels when food intake was decreased, and chemogenetic manipulation of DVC astrocytes ...
K. Selin Ozkaya +4 more
wiley +1 more source

