Results 161 to 170 of about 106,627 (314)

Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 186-197, January 2023., 2023
ABSTRACT Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ERα (Ot‐ERα) regulated trabecular, but not ...
Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxim A. Gallant, Claes Ohlsson, Teresita M. Bellido, Russell P. Main   +6 more
wiley   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Dietary yolk supplementation decreases rates of yolk deposition in Japanese quail

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 339, Issue 1, Page 63-73, January 1, 2023., 2023
Dietary supplementation with egg yolk decreases the rate of yolk deposition in quail. Quail with high body condition indices deposit yolk more slowly. Abstract Generation of egg yolk by birds requires the synthesis and deposition of large amounts of protein and lipid, and is often accompanied by the incorporation of additional physiological mediators ...
Kristen J. Navara, Kylie Graden, Mary T. Mendonça   +2 more
wiley   +1 more source

A concise review of testosterone and bone health

Clinical Interventions in Aging, 2016
Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman, Kok-Yong Chin Department of Pharmacology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lampur, Malaysia Abstract: Osteoporosis is a condition causing significant morbidity and mortality in the elderly
Mohamad NV, Soelaiman IN, Chin KY
doaj  

Prognostic markers in quadruple negative breast cancer

Journal of BioScience and Biotechnology, 2023
Quadruple-negative breast cancer (QNBC) presents with negative expression of estrogen, progesterone, and androgen receptors and of human epidermal growth factor receptor 2. This BC subtype has the worst prognosis. In QNBC, there is a
Galina Yaneva, Tsonka Dimitrova, Stoyan Stoyanov, Nikoleta Ivanova, Galina Nenkova, Djeni Cherneva, Petya Boycheva, Dobri Ivanov   +7 more
doaj  

Correlation between the presence of the nuclear AR-V7 androgen receptor and clinical evolution of prostate cancer: in vitro analysis of a combination of compounds targeting PI3K [PDF]

, 2019
Introduzione: PCa è una malattia multiforme e biologicamente molto eterogenea. Diversi meccanismi chiave nella progressione della malattia da androgeno-dipendente ad androgeno-indipendente (CRCP) possono essere attribuiti ad alterazione nella via di ...
Cattarino, Susanna
core  

Accuracy of direct gradient sensing by cell-surface receptors [PDF]

arXiv, 2009
Chemotactic cells of eukaryotic organisms are able to accurately sense shallow chemical concentration gradients using cell-surface receptors. This sensing ability is remarkable as cells must be able to spatially resolve small fractional differences in the numbers of particles randomly arriving at cell-surface receptors by diffusion.
arxiv  

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

Androgen receptor α peak expression in retina rather than gonad of Hainan medaka, Oryzias curvinotus

Reproduction and Breeding, 2022
Androgen is a member of the sex steroid hormones family which plays an important role in the development and maturation of the vertebrate reproductive system.
Zhongduo Wang, Aiping Deng, Jiahui Huang, Shunkai Huang, Gyamfua Afriyie, Zhongdian Dong, Yusong Guo   +6 more
doaj  

Androgen receptor dysfunction in human androgen insensitivity

Trends in Endocrinology & Metabolism, 1995
The androgen insensitivity syndromes comprise a spectrum of phenotypic abnormalities in male sex differentiation and development that result from target tissue resistance to androgen action due to molecular lesions in the X-chromosome-linked androgen receptor gene.
openaire   +3 more sources