Results 171 to 180 of about 669,213 (305)

Progress in the Application of Exosomes in Androgenetic Alopecia: Focusing on Molecular Mechanisms. [PDF]

Int J Nanomedicine
Chen Y, Chen S, Ding W, Li L, Li P, Li Z, Zhou N.   +6 more
europepmc   +1 more source

Low‐Dose Chlorothalonil Induces Testicular Injury Through Disruption of Steroidogenic Signaling in Adult Male Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorothalonil (CHL) is a widely used organochlorine fungicide frequently detected in environmental and food matrices. Although increasing evidence indicates adverse effects in nontarget species, the mechanisms underlying CHL‐induced male reproductive toxicity remain incompletely understood.
Cristiana Livramento Oliveira Pinto, Nicoly Caixêta Gonçalves, Paula Rafaela Queiroz da Silva, Ludmila Rodrigues Pontes, Juliana Reis Machado, Virmondes Rodrigues Jr., Hugo Felix Perini, Gláucia Eloisa Munhoz de Lion Siervo   +7 more
wiley   +1 more source

Sex hormones and their receptors in osteoarthritis: current research progress. [PDF]

Ann Jt
Wang Z, Shi X, Yang G, Zheng K, Xu R.
europepmc   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

Clascoterone in the Treatment of Acne Vulgaris: A Narrative Review. [PDF]

Pharmaceuticals (Basel)
Shefa S, Szwach J, Karwowska A, Wojno A, Łyko M.   +4 more
europepmc   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

LHCGR phamacodynamic effects during follicular maturation. [PDF]

Front Endocrinol (Lausanne)
Perri C, Casarini L, Lazzaretti C.
europepmc   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci, Cansu Ozbayer, Ata Ozen, Gamze Zengin, Hulyam Kurt   +4 more
wiley   +1 more source

Lycopene ameliorates acrylamide-induced reproductive toxicity through enhancement in testicular antioxidant status and upregulation of androgen receptor expression in male Wistar rats. [PDF]

BMC Pharmacol Toxicol
Adebodun GO, Obabolujo TB, Adesope PE, Onyeacholem E, Raji Y.   +4 more
europepmc   +1 more source

Establishment Reference Intervals Using the Kosmic Algorithm for Hemoglobin Levels and Platelet, Red Blood Cell, and White Blood Cell Counts

Journal of Clinical Laboratory Analysis, EarlyView.
Using kosmic algorithm and SDR analysis of real‐world data from 4795 adults in Xinjiang, we established population‐specific CBC reference intervals requiring sex stratification for RBC/HGB, ethnicity stratification for PLT, and no stratification for WBC.
Chunyan Liu, Zhaohui Deng, Yingbo Song, Wenli Wu, Yan Li, Fang Yang, Huimin Liu, Xin Zhang   +7 more
wiley   +1 more source