Results 181 to 190 of about 106,627 (314)

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

The effects of endocrine‐disrupting chemicals on ovarian‐ and ovulation‐related fertility outcomes

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 608-631, December 2022., 2022
Abstract Exposure to endocrine‐disrupting chemicals (EDCs) is unavoidable, which represents a public health concern given the ability of EDCs to target the ovary. However, there is a large gap in the knowledge about the impact of EDCs on ovarian function, including the process of ovulation.
Katie L. Land   +3 more
wiley   +1 more source

The Impact of Triptorelin on Hormone Levels in Human and Its Metabolite Confirmation Using Liquid Chromatography–Ion Trap/Time‐of‐Flight Mass Spectrometry (LC/MS‐IT‐TOF) and Liquid Chromatography–Orbitrap (LC‐Orbitrap) for Doping Control Analysis

open access: yesDrug Testing and Analysis, EarlyView.
Triptorelin (5–10) confirmation using LC/MS‐IT‐TOF and LC‐Orbitrap can be used as evidence of triptorelin abuse in doping control. ABSTRACT Triptorelin, a synthetic gonadotrophin‐releasing hormone (GnRH), is mainly used in the clinical treatment of prostate cancer.
Navaporn Saardpun   +6 more
wiley   +1 more source

Biology and Management of Male‐Bodied Athletes in Elite Female Sports

open access: yesDrug Testing and Analysis, EarlyView.
Graphical representation of the relationships of transgender and XY DSDF as male‐bodied athletes along the binary dimensions of biological sex. ABSTRACT The physical advantages in elite power sports that allow men to surpass women are derived from the experience of male puberty.
David J. Handelsman, Stéphane Bermon
wiley   +1 more source

Effects of the Dietary Supplement 5α‐Hydroxy‐Laxogenin in the Orchiectomized Rat Model

open access: yesDrug Testing and Analysis, EarlyView.
The dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated in the castrated male rat for potential androgenic and anabolic effects. Moreover, androgen receptor binding of 5α‐hydroxy‐laxogenin was modelled by in silico docking. While molecular modelling supports androgen receptor binding, we observed neither androgenic nor anabolic effects ...
Daniel Derwand   +4 more
wiley   +1 more source

Prostate cancer aggressiveness and financial toxicity among prostate cancer patients

open access: yesThe Prostate, Volume 83, Issue 1, Page 44-55, January 1, 2023., 2023
Abstract Introduction Financial toxicity (FT) is a growing concern among cancer survivors that adversely affects the quality of life and survival. Individuals diagnosed with aggressive cancers are often at a greater risk of experiencing FT. The objectives of this study were to estimate FT among prostate cancer (PCa) survivors after 10−15 years of ...
Madhav KC   +13 more
wiley   +1 more source

Sports Supplement Analysis Survey for the Prevalence of WADA Prohibited Substances in the Australian Online Marketplace

open access: yesDrug Testing and Analysis, EarlyView.
A survey of 200 sports supplements purchased online in Australia and analysed for WADA Prohibited Substances. Athlete education regarding the use of sports supplements remains a high priority as 35% of the products contained WADA Prohibited Substances. ABSTRACT Sports supplements are used extensively by people involved in competitive sports. However, a
Louise Barker   +4 more
wiley   +1 more source

Metformin use and mortality in Asian, diabetic patients with prostate cancer on androgen deprivation therapy: A population‐based study

open access: yesThe Prostate, Volume 83, Issue 1, Page 119-127, January 1, 2023., 2023
Abstract Background This study aims to examine the associations between metformin use concurrent with androgen deprivation therapy (ADT) and mortality risks in Asian, diabetic patients with prostate cancer (PCa). Methods This study identified diabetic adults with PCa receiving any ADT attending public hospitals in Hong Kong between December 1999 and ...
Yan Hiu Athena Lee   +8 more
wiley   +1 more source

Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis

open access: yesESC Heart Failure, EarlyView.
Abstract COVID‐19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID‐19 vaccines and death from myocarditis using post‐mortem analysis.
Nicolas Hulscher   +3 more
wiley   +1 more source

Presence of cells in the polyaneuploid cancer cell (PACC) state predicts the risk of recurrence in prostate cancer

open access: yesThe Prostate, Volume 83, Issue 3, Page 277-285, February 15, 2023., 2023
Abstract Background The nonproliferating polyaneuploid cancer cell (PACC) state is associated with therapeutic resistance in cancer. A subset of cancer cells enters the PACC state by polyploidization and acts as cancer stem cells by undergoing depolyploidization and repopulating the tumor cell population after the therapeutic stress is relieved.
Levent Trabzonlu   +4 more
wiley   +1 more source

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