Results 51 to 60 of about 1,004,480 (189)

Ligand Recognition Determines the Role of Inhibitory B Cell Co-receptors in the Regulation of B Cell Homeostasis and Autoimmunity

open access: yesFrontiers in Immunology, 2018
B cells express various inhibitory co-receptors including CD22, CD72, and Siglec-G. These receptors contain immunoreceptor tyrosine-based inhibition motifs (ITIMs) in the cytoplasmic region.
Takeshi Tsubata
doaj   +1 more source

A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons

open access: yesBMC Immunology, 2023
Background The anglerfish, belonging to the teleost order Lophiiformes, are a diverse and species-rich group of fish that are known to exhibit a number of unique morphological, reproductive and immunological adaptations.
Jeremy B. Swann   +3 more
doaj   +1 more source

Superantigen Recognition and Interactions: Functions, Mechanisms and Applications

open access: yesFrontiers in Immunology, 2021
Superantigens are unconventional antigens which recognise immune receptors outside their usual recognition sites e.g. complementary determining regions (CDRs), to elicit a response within the target cell.
Anthony M. Deacy   +3 more
doaj   +1 more source

Modeling viral coevolution: HIV multi-clonal persistence and competition dynamics [PDF]

open access: yes, 2005
The coexistence of different viral strains (quasispecies) within the same host are nowadays observed for a growing number of viruses, most notably HIV, Marburg and Ebola, but the conditions for the formation and survival of new strains have not yet been ...
Altfeld   +43 more
core   +2 more sources

B cell antigen receptor signaling and internalization are mutually exclusive events.

open access: yesPLoS Biology, 2006
Engagement of the B cell antigen receptor initiates two concurrent processes, signaling and receptor internalization. While both are required for normal humoral immune responses, the relationship between these two processes is unknown.
Ping Hou   +8 more
doaj   +1 more source

The Immune System [PDF]

open access: yes, 1995
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut   +1 more
core   +1 more source

Memory control by the B cell antigen receptor

open access: yesImmunological Reviews, 2018
SummaryThe generation of memory B cells (MBCs) that have undergone immunoglobulin class switching from IgM, which dominates primary antibody responses, to other immunoglobulin isoforms is a hallmark of immune memory. Hence, humoral immunological memory is characterized by the presence of serum immunoglobulins of IgG subtypes known as the γ‐globulin ...
Niklas Engels, Jürgen Wienands
openaire   +3 more sources

Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles. [PDF]

open access: yes, 2006
Hepatic sinusoidal endothelial cells are unique among endothelial cells in their ability to internalize and process a diverse range of antigens. DC-SIGNR, a type 2 C-type lectin expressed on liver sinusoids, has been shown to bind with high affinity to ...
Adam Jennings   +61 more
core   +2 more sources

The yin and yang of Fcγ receptors in ITP [PDF]

open access: yes, 2008
The Fcγ receptors contribute to the susceptibility to autoimmune diseases such as ITP in several ways: (1) they modulate dendritic cell antigen processing and presentation, (2) they modulate antibody production by B cells, and (3) they participate in ...
McKenzie, Steven E.
core   +1 more source

Isotype Specific Assembly of B Cell Antigen Receptors and Synergism With Chemokine Receptor CXCR4

open access: yesFrontiers in Immunology, 2018
Expression of the membrane-bound form of the immunoglobulin (Ig) as part of the antigen receptor is indispensable for both the development and the effector function of B cells.
Palash C. Maity   +3 more
doaj   +1 more source

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