Results 181 to 190 of about 9,580 (229)
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Mechanism of decreased intestinal calcitriol receptor concentration in renal failure
American Journal of Physiology-Renal Physiology, 1993The biological actions of calcitriol and its receptor synthesis are believed to be mediated through the calcitriol-receptor complex interacting with nuclear chromatin of target cells. Thus inhibition of the receptor interaction with DNA could diminish the biological actions of calcitriol and upregulation of its receptor.
C H, Hsu, S R, Patel, R, Vanholder
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Calcitriol-resistant rickets due to vitamin D receptor defects
Trends in Endocrinology & Metabolism, 1995Calcitriol-resistant rickets (CRR) is an autosomal recessive disease due to a defect in the vitamin D receptor (VDR) or a site distal to it. The main characteristics are extreme rickets, with growth attenuation, osteomalacia, secondary hyperparathyroidism, severe dental caries, and alopecia.
Z, Hochberg, Y, Weisman
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Calcitriol receptors in rat thyroid follicular cells (FRTL-5)
Acta Endocrinologica, 1991Abstract. The FRTL-5 cell line is widely used as a model for normal thyroid follicular cells. These cells have retained their ability to alter cAMP production, cell proliferation, iodine uptake, and thyroglobulin synthesis in response to thyrotropin. We have previously shown that calcitriol attenuated both basal and TSH stimulated cAMP production dose ...
J P, Berg, P A, Torjesen, E, Haug
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Biochemical and Biophysical Research Communications, 1996
Human intestinal mucosa consists of highly active epithelial cells in continual renewal and differentiation processes anatomically located at different portions of the villi. Besides its well recognized role in bone cell homeostasis, calcitriol has been attributed a role in cellular differentiation and proliferation in normal and cancerous cells.
E E, Delvin +3 more
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Human intestinal mucosa consists of highly active epithelial cells in continual renewal and differentiation processes anatomically located at different portions of the villi. Besides its well recognized role in bone cell homeostasis, calcitriol has been attributed a role in cellular differentiation and proliferation in normal and cancerous cells.
E E, Delvin +3 more
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Effects of calcitriol upon TGF-βs and their receptors in trophoblast cells
Journal of Reproductive ImmunologyCalcitriol levels increase during pregnancy, contributing to the hormonal and immunological balance, but its deficiency has been associated with problems during this period. Meanwhile, transforming growth factors-β (TGF-βs) play an important role in the maintenance of fetal-maternal immune tolerance; however, exacerbated concentrations of this growth ...
Nancy Noyola-Martínez +8 more
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Calcitriol modulates receptor for advanced glycation end products (RAGE) in diabetic hearts
International Journal of Cardiology, 2014Receptor for advanced glycation end products (RAGE) signaling pathway plays a vital role in diabetic cardiovascular complications. Calcitriol has been shown to exert various beneficial cardiovascular effects. The purpose of this study is to determine whether calcitriol can modulate RAGE expression, and study the potential mechanisms in diabetic hearts ...
Ting-Wei, Lee +5 more
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Journal of Steroid Biochemistry, 1985
In the present study we have examined the developmental changes in the concentration of receptors for calcitriol in high-salt cytosol from the rat testis. Receptors for calcitriol were undetectable (less than 0.4 fmol/mg protein) until day 24, after which there was a rapid increase to reach adult levels (6-8 fmol/mg protein) between day 50-60. The lack
F O, Levy +5 more
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In the present study we have examined the developmental changes in the concentration of receptors for calcitriol in high-salt cytosol from the rat testis. Receptors for calcitriol were undetectable (less than 0.4 fmol/mg protein) until day 24, after which there was a rapid increase to reach adult levels (6-8 fmol/mg protein) between day 50-60. The lack
F O, Levy +5 more
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Bone, 1990
The content and affinity of calcitriol receptors were analyzed in cultured osteoblasts from normal and hypophosphatemic mice. Hypertonic cell extracts were prepared by sonication followed by centrifugation at 200,000 g x 30 min. Analysis, at saturating levels of labeled 1,25(OH)2D3, revealed that binding of the hormone was dependent on the density of ...
E E, Delvin +4 more
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The content and affinity of calcitriol receptors were analyzed in cultured osteoblasts from normal and hypophosphatemic mice. Hypertonic cell extracts were prepared by sonication followed by centrifugation at 200,000 g x 30 min. Analysis, at saturating levels of labeled 1,25(OH)2D3, revealed that binding of the hormone was dependent on the density of ...
E E, Delvin +4 more
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Acta Endocrinologica, 1992
Vitamin D metabolites in serum and calcitriol receptor concentration in parathyroid tissue were examined in 52 patients operated on for primary hyperparathyroidism. The calcitriol receptor levels were not different in parathyroid adenomas (mean 224 fmol/mg of protein, range 29–509, N = 43), normal parathyroid tissue (mean 245, range 31–690, N = 20 ...
T, Trydal +5 more
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Vitamin D metabolites in serum and calcitriol receptor concentration in parathyroid tissue were examined in 52 patients operated on for primary hyperparathyroidism. The calcitriol receptor levels were not different in parathyroid adenomas (mean 224 fmol/mg of protein, range 29–509, N = 43), normal parathyroid tissue (mean 245, range 31–690, N = 20 ...
T, Trydal +5 more
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The expression of receptors for IgA on human monocytes and calcitriol-treated HL-60 cells.
The Journal of Immunology, 1985Abstract In this study, we investigated the expression of IgA Fc receptors (FcR alpha) by human myeloid cells. By using a sensitive cytofluorometric IgA binding assay, we found that approximately 85% of peripheral blood monocytes bound IgA in an isotype-specific fashion.
C R, Maliszewski, L, Shen, M W, Fanger
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