Results 211 to 220 of about 56,351 (295)

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Fenebrutinib and Effect on the QT/QTc Interval in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Fenebrutinib is a Bruton's tyrosine kinase inhibitor under investigation for the treatment of multiple sclerosis. The goal of this study was to investigate the effect of fenebrutinib on cardiac repolarization (QT interval) as well as its safety, tolerability, and pharmacokinetics in healthy participants.
Yan Xu, Sonoko Kawakatsu, Denison Kuruvilla, John N. Ratchford, Qi Qi, Malgorzata Sierzega, Lin Pan, Jiajie Yu   +7 more
wiley   +1 more source

Clinical guidelines highlight for the hospitalist: Management of cyclic vomiting syndrome in children

Journal of Hospital Medicine, Volume 21, Issue 3, Page 291-293, March 2026.
Yamileth N. Hernandez, Hannah M. Gardner
wiley   +1 more source

‘SASADECC’—A Unique Model of Collaborative Care Between Government and Non‐Government Health Services for Adolescents With Complex Substance Use Issues

Drug and Alcohol Review, Volume 45, Issue 3, March 2026.
ABSTRACT Introduction Despite the importance of early intervention, major treatment gaps exist for adolescents with substance use issues. This report describes a unique collaboration between government and non‐government health services—The Specialist Addiction Service for Adolescents (SASA) adolescent addiction psychiatry service and Sydney Drug ...
David E. A. Gordon, Belinda Volkov, Arezu Akbarian, Lauren A. Monds, Mark Montebello   +4 more
wiley   +1 more source

Medical Cannabis for Best Supportive Care of Patients Affected by Cancers of the Head and Neck: A Narrative Review. [PDF]

In Vivo
Perri F, Marciano ML, Zotta A, Pontone M, Piccirillo A, Casale M, DI Filippo P, Sarno MR, D' Aniello R, Cascella M, Maiolino P.   +10 more
europepmc   +1 more source

Study participant impression of use and satisfaction with STS101 (dihydroergotamine nasal powder): Results from the open‐label ASCEND acute migraine study

Headache: The Journal of Head and Face Pain, Volume 66, Issue 3, Page 688-696, March 2026.
Abstract Objective/Background This study was undertaken to assess participants' impression of use and satisfaction with STS101 in a long‐term, open‐label safety study. The ASCEND study assessed the safety and tolerability of STS101, an investigational drug–device combination of 5.2 mg dihydroergotamine in a single‐use nasal delivery device for the ...
Jessica Ailani, Larry Charleston IV, Shannon Strom, Detlef Albrecht, Robert Cowan   +4 more
wiley   +1 more source

Dual Role of the Spinal Endocannabinoid System in Response to Noxious Stimuli: Antinociceptive Pathways and Neuropathic Pain Mechanisms. [PDF]

Int J Mol Sci
Saldaña R, Carrascosa AJ, Torregrosa AB, Navarrete F, García-Gutiérrez MS, Manzanares J.   +5 more
europepmc   +1 more source

The role of accessory proteins and co‐factors in regulation of melanocortin‐4 receptor signalling: An update

Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract The melanocortin‐4 receptor (MC4R) is a G protein‐coupled receptor with an essential role in appetite suppression and energy homeostasis. Genetic mutations in the receptor and components of its signalling pathway that cause obesity in humans, dogs and rodent models have revealed important insights into how the receptor signals and what ...
Aqfan Jamaluddin, Alyce McClellan, Eleanor Raffan, Caroline M. Gorvin   +3 more
wiley   +1 more source

Cannabinoids: Medicine or Poison [PDF]

Balkan Med J
Karal Y.
europepmc   +1 more source