Results 41 to 50 of about 579,297 (292)

Effects of Cannabidiol‐Rich Cannabis Oil on Facial Expression Recognition and Theory of Mind in Children With Autism Spectrum Disorder: A Randomized Clinical Trial

Autism Research, EarlyView.
ABSTRACT To evaluate, in a post hoc subanalysis, the effects of cannabidiol (CBD)‐rich cannabis oil on facial expression recognition and theory of mind in children with autism spectrum disorder (ASD). This post hoc subanalysis included children from a double‐blind, randomized, placebo‐controlled trial who completed social cognition assessments at ...
Wandersonia Moreira Brito Medeiros, Estácio Amaro da Silva Junior, Katy Lísias Gondim Dias de Albuquerque, Marine Diniz da Rosa, Amanda Gleiciane de Lima Oliveira, Maycon Jônatas da Silva, João Vitor Andrade Fernandes, Emily Caroline Costa Vieira, João Paulo Mendes dos Santos, Thais Cavalcanti Borges, Ana Hermínia Andrade e Silva, Carlos Espínola Neto Segundo, Nelson Torro‐Alves   +12 more
wiley   +1 more source

Dendritic Cell Regulation by Cannabinoid-Based Drugs

Pharmaceuticals, 2010
Cannabinoid pharmacology has made important advances in recent years after the cannabinoid system was discovered. Studies in experimental models and in humans have produced promising results using cannabinoid-based drugs for the treatment of obesity and ...
Mattias Svensson, Puran Chen, Oscar Hammarfjord   +2 more
doaj   +1 more source

Cannabinoid type 1 receptors transiently silence glutamatergic nerve terminals of cultured cerebellar granule cells. [PDF]

PLoS ONE, 2014
Cannabinoid receptors are the most abundant G protein-coupled receptors in the brain and they mediate retrograde short-term inhibition of neurotransmitter release, as well as long-term depression of synaptic transmission at many excitatory synapses.
Jorge Ramírez-Franco, David Bartolomé-Martín, Beatris Alonso, Magdalena Torres, José Sánchez-Prieto   +4 more
doaj   +1 more source

Cannabinoid Signaling in Auditory Function and Development

Frontiers in Molecular Neuroscience, 2021
Plants of the genus Cannabis have been used by humans for millennia for a variety of purposes. Perhaps most notable is the use of certain Cannabis strains for their psychoactive effects.
Sumana Ghosh, Kendra Stansak, Bradley J. Walters, Bradley J. Walters   +3 more
doaj   +1 more source

Serum contents of endocannabinoids are correlated with blood pressure in depressed women. [PDF]

, 2012
BACKGROUND: Depression is known to be a risk factor for cardiovascular diseases but the underlying mechanisms remain unclear. Since recent preclinical evidence suggests that endogenous agonists of cannabinoid receptors (endocannabinoids) are involved in ...
Ho, WS V, Miller, GE, Hillard, CJ, Ho WS Vanessa, WS Vanessa Ho, Hillard, Cecilia J., Gorzalka, Boris B., Miller, Gregory E, Hill Matthew N, Hillard Cecilia J, Hill, MN, Gorzalka, Boris B, Gregory E Miller, Hill, Matthew N, Miller Gregory E, Hillard, Cecilia J, Ho, Vanessa, Miller, Gregory E., Matthew N Hill, Gorzalka, BB, Boris B Gorzalka, Cecilia J Hillard, Hill, Matthew N., Gorzalka Boris B, Ho, WS   +24 more
core   +1 more source

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

Local activation of cannabinoid CB₁ receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents

Molecular Pain, 2011
Background Systemic administration of cannabinoid agonists is known to reduce pain induced by bladder inflammation and to modulate cystometric parameters in vivo.
Cervero Fernando, Walczak Jean-Sébastien   +1 more
doaj   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

The Expression of Cannabinoid and Cannabinoid-Related Receptors on the Gustatory Cells of the Piglet Tongue

Molecules
The gustatory system is responsible for detecting and evaluating the palatability of the various chemicals present in food and beverages. Taste bud cells, located primarily on the tongue, communicate with the gustatory sensory neurons by means of ...
Rodrigo Zamith Cunha, Ester Grilli, Andrea Piva, Cecilia Delprete, Cecilia Franciosi, Marco Caprini, Roberto Chiocchetti   +6 more
doaj   +1 more source

Novel cannabinoid receptors [PDF]

British Journal of Pharmacology, 2007
Cannabinoids have numerous physiological effects. In the years since the molecular identification of the G protein‐coupled receptors CB1 and CB2, the ion channel TRPV1, and their corresponding endogenous ligand systems, many cannabinoid‐evoked actions have been shown conclusively to be mediated by one of these specific receptor targets.
openaire   +2 more sources