Results 131 to 140 of about 2,880,433 (308)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Functional Divergence for N-Linked Glycosylation Sites in Equine Lutropin/Choriogonadotropin Receptors. [PDF]

Curr Issues Mol Biol
Byambaragchaa M, Kang HJ, Park SH, Shin MG, Won KM, Kang MH, Min KS.   +6 more
europepmc   +1 more source

Human NK cells: surface receptors, inhibitory checkpoints, and translational applications

Cellular & Molecular Immunology, 2019
S. Sivori, P. Vacca, Genny Del Zotto, E. Munari, M. Mingari, L. Moretta   +5 more
semanticscholar   +1 more source

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source

Conversion of natural cytokine receptors into orthogonal synthetic biosensors. [PDF]

Nat Chem Biol
Edelstein HI, Cosio A, Ezekiel ML, Corcoran WK, Morris AH, Leonard JN.   +5 more
europepmc   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

The role of mast cells in allergic rhinitis. [PDF]

PeerJ
Zhang J, Xie X, Ma R, Liu P.
europepmc   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Targeting GABA signaling in the tumor microenvironment: implications for immune cell regulation and immunotherapy resistance. [PDF]

Front Immunol
Zhao Y, Xu J, Yang K, Bao L.
europepmc   +1 more source

Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters.

Proceedings of the National Academy of Sciences of the United States of America, 1994
M. Kavanaugh, Daniel G. Miller, Daniel G. Miller, Weibin Zhang, Wendy Law, Wendy Law, S. Kozak, D. Kabat, A. Miller, A. Miller   +9 more
semanticscholar   +1 more source