Results 11 to 20 of about 743,802 (291)

The Small GTPase OsRac1 Forms Two Distinct Immune Receptor Complexes Containing the PRR OsCERK1 and the NLR Pit [PDF]

, 2021
Plants employ two different types of immune receptors, cell surface pattern recognition receptors (PRRs) and intracellular nucleotide-binding and leucine-rich repeat-containing proteins (NLRs), to cope with pathogen invasion.
Hamada, Satoshi, Kaneko-Kawano, Takako, Shimamoto, Ko, Yao, Ai, Akamatsu, Akira, Kosami, Ken-ichi, Fukada, Fumi, Kawano, Yoji, Dang, Thu Thi, Wang, Qiong, Fujiwara, Masayuki, Wakabayashi, Megumi   +11 more
core   +4 more sources

Inhibition of lysosomal activity by Baf-A1 prevented TRAIL and bortezomib induced DR4 internalization. [PDF]

, 2014
(A) DR4 and DR5 receptors cell surface expression was analyzed in HCT116 p53−/− cells pretreated with Baf-A1 (25 µM) for 1 h following bortezomib (1 nM) and TRAIL (1 ng/ml) treatment alone or in combination for 24 h. (B) Viability of the cells treated as
Maxim L. Bychkov (643646), Dmitry A. Dolgikh (472251), Marine E. Gasparian (472249), Mikhail P. Kirpichnikov (472252)   +3 more
core   +1 more source

Osteoclast receptors and signaling [PDF]

, 2008
Osteoclasts are bone-resorbing cells derived from hematopoietic precursors of the monocyte-macrophage lineage. Besides the well known Receptor Activator of Nuclear factor-kappa B (RANK), RANK ligand and osteoprotegerin axis, a variety of factors tightly ...
TETI, ANNA MARIA, RUCCI, Nadia, Del Fattore A   +2 more
core   +1 more source

Characterisation of the adiponectin receptors: Cell-surface expression and signal transduction of AdipoR1 and AdipoR2 are palmitoylation-dependent [PDF]

, 2014
The adiponectin axis is a major regulator of metabolic, cardiovascular and inflammatory tone. Current understanding of the adiponectin receptors, R1 and R2, is rudimentary constraining our ability to target these atypical seven transmembrane receptors ...
Henstridge, Darren, Febbraio, Mark A., Hooper, John, Whitehead, Jonathan P, Keshvari, Sahar, O'Neill, Hayley M., Adams, Mark   +6 more
core   +1 more source

The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background A hallmark of heart failure is cardiac fibrosis, which results from the injury‐induced differentiation response of resident fibroblasts to myofibroblasts that deposit extracellular matrix.
Nicholas W. Chavkin, Soichi Sano, Ying Wang, Kosei Oshima, Hayato Ogawa, Keita Horitani, Miho Sano, Susan MacLauchlan, Anders Nelson, Karishma Setia, Tanvi Vippa, Yosuke Watanabe, Jeffrey J. Saucerman, Karen K. Hirschi, Noyan Gokce, Kenneth Walsh   +15 more
doaj   +1 more source

Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application

Haematologica, 2008
Background Donor lymphocyte infusion is an effective form of adoptive immunotherapy for hematologic malignancies after allogeneic stem cell transplantation.
Marieke Griffioen, H.M. Esther van Egmond, Helen Barnby-Porritt, Menno A.W.G. van der Hoorn, Renate S. Hagedoorn, Michel G.D. Kester, Nikolai Schwabe, Roel Willemze, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk   +9 more
doaj   +1 more source

Research Progress of Dendritic Cell Surface Receptors and Targeting

Biomedicines, 2023
Dendritic cells are the only antigen-presenting cells capable of activating naive T cells in humans and mammals and are the most effective antigen-presenting cells.
Chunyu Tong, Yimin Liang, Xianle Han, Zhelin Zhang, Xiaohui Zheng, Sen Wang, Bocui Song   +6 more
doaj   +1 more source

Inhibition of bortezomib and TRAIL induced DR4 internalization by E-64 in HCT116 p53^−/− cells. [PDF]

, 2014
(A) DR4 and DR5 receptors cell surface expression was analyzed after incubation of the cells with E-64 (25 µM) for 1 h following medium change and treatment with TRAIL (1 ng/ml), bortezomib (1 nM) or in combination of the two drugs for 24 h.
Maxim L. Bychkov (643646), Dmitry A. Dolgikh (472251), Marine E. Gasparian (472249), Mikhail P. Kirpichnikov (472252)   +3 more
core   +1 more source

A generic cell surface ligand system for studying cell-cell recognition.

PLoS Biology, 2019
Dose-response experiments are a mainstay of receptor biology studies and can reveal valuable insights into receptor function. Such studies of receptors that bind cell surface ligands are currently limited by the difficulty in manipulating the surface ...
Eleanor M Denham, Michael I Barton, Susannah M Black, Marcus J Bridge, Ben de Wet, Rachel L Paterson, P Anton van der Merwe, Jesse Goyette   +7 more
doaj   +1 more source

Gene expression profile of vitamin D3 treated HL60 cells shows an incomplete molecular phenotypic conversion to monocytes [PDF]

, 2002
By high density oligonucleotide microarrays we have studied the expression profile of proliferating and VD treated HL60 cells and the molecular phenotype of VD monocytes and that of CD14+ peripheral monocytes has been compared.
A. Bergamaschi, TAGLIAFICO, Enrico, Tagliafico, E., C Gemelli, E Tenedini, U. Torelli, A Bergamaschi, Tenedini, E., M Siena, S Ferrari, TENEDINI, Elena, Siena, M., Manfredini, R., E Tagliafico, U Torelli, PERCUDANI, Riccardo, R. Percudani, T Zanocco-Marani, Grande, A., ZANOCCO MARANI, Tommaso, R Percudani, A Grande, M Montanari, Ferrari, S., R Manfredini, Bergamaschi, A., M. Montanari, C. Gemelli, Torelli, U., M. Siena, Montanari, M., GRANDE, Alexis, FERRARI, Sergio, Zanocco Marani, T., Gemelli, C., MANFREDINI, Rossella   +35 more
core   +1 more source