Results 41 to 50 of about 10,017,512 (298)
L1CAM binds ErbB receptors through Ig-like domains coupling cell adhesion and neuregulin signalling. [PDF]
, 2012 During nervous system development different cell-to-cell communication mechanisms operate in parallel guiding migrating neurons and growing axons to generate complex arrays of neural circuits.
Carmen Grijota-Martinez (152374) +20 more
core +1 more source
Platelet Apoptosis Can Be Triggered Bypassing the Death Receptors
Clinical and Applied Thrombosis/Hemostasis, 2019 In nucleated cells, the extrinsic pathway of the programmed cell death (apoptosis) is triggered by interaction of death ligands of the tumor necrosis factor superfamily with the death receptors on external cell surface membrane.
Valery Leytin PhD +2 more
doaj +1 more source
Expanding functions of lipoprotein receptors
Journal of Lipid Research, 2009 Lipoprotein receptors are evolutionarily ancient proteins that are expressed on the surface of many cell types. Beginning with the appearance of the first primitive multicellular organisms, several structurally and functionally distinct families of ...
Joachim Herz +3 more
doaj +1 more source
Viral destruction of cell surface receptors [PDF]
Proceedings of the National Academy of Sciences, 2008 Viral infection is initiated by the attachment of the virus to the appropriate host cells. This process involves a series of dedicated virion proteins that have evolved to specifically recognize one, or a small number, of cell-surface molecules.
Andrew D, Mesecar, Kiira, Ratia
openaire +2 more sources
The role of the chemokine receptor CXCR4 in oral squamous cell carcinoma metastasis [PDF]
, 2010 PhDOral Squamous Cell Carcinoma (OSCC) is the sixth most common cancer worldwide. The greatest cause of mortality and surgical morbidity is due to the common spread of tumour cells from the primary lesion to the lymph nodes of the neck. This pathway is
Collier, Jonathan Marc
core +4 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue [PDF]
, 2004 Identification of cellular factors involved in HIV-1 entry and transmission at mucosal surfaces is critical for understanding viral pathogenesis and development of effective prevention strategies. Here we describe the evaluation of HIV-1 entry inhibitors
Ines Frank +26 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Zhongguo shuxue zazhi, 2023 Objective To investigate the effect of immunoglobulin G (IgG) dimer concentration of intravenous immunoglobulin (IVIG) on the binding ability of IgG Fc fragment to THP-1 cell surface receptors.
Tingting LEI +5 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source