Results 31 to 40 of about 10,017,512 (298)

A Robust and Rapid Method of Producing Soluble, Stable, and Functional G-Protein Coupled Receptors [PDF]

, 2011
Membrane proteins, particularly G-protein coupled receptors (GPCRs), are notoriously difficult to express. Using commercial E.coli cell-free systems with the detergent Brij-35, we could rapidly produce milligram quantities of 13 unique GPCRs ...
Braun, Dieter, Shuguang Zhang, Baaske Philipp, Moran Jerabek-Willemsen, Geissler, Sandra, Duhr, Stefan, Duhr Stefan, Corin, Karolina A., Sandra Geissler, Wienken Christoph J., Christoph J. Wienken, Geissler Sandra, Jerabek-Willemsen, Moran, Christoph J Wienken, Zhang Shuguang, Stefan Duhr, Emily Brown, Wang Xiaoqiang, Philipp Baaske, Deepali B. Ravel, Brown, Emily, Song Junyao, Xiaoqiang Wang, Braun Dieter, Karolina Corin, Junyao Song, Wang, Xiaoqiang, Dieter Braun, Baaske, Philipp, Wienken, Christoph J., Ravel Deepali B., Corin, Karolina, Ravel, Deepali B., Brown Emily, Song, Junyao, Jerabek-Willemsen Moran, Corin Karolina, Zhang, Shuguang, Deepali B Ravel, Brown, Emily E., Ra Geissler   +40 more
core   +1 more source

Interaction of KSHV with Host Cell Surface Receptors and Cell Entry

Viruses, 2014
Virus entry is a complex process characterized by a sequence of events. Since the discovery of KSHV in 1994, tremendous progress has been made in our understanding of KSHV entry into its in vitro target cells.
Mohanan Valiya Veettil, Chirosree Bandyopadhyay, Dipanjan Dutta, Bala Chandran   +3 more
doaj   +1 more source

Aggregation Limits Surface Expression of Homomeric GluA3 Receptors [PDF]

, 2016
AMPA receptors are glutamate-gated cation channels assembled from GluA1-4 subunits and have properties that are strongly dependent on the subunit composition.
Coleman, S.K., Hou, Y., Semenov, A., Keinänen, K., Willibald, M., Moykkynen, T.   +5 more
core   +1 more source

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL

Frontiers in Cell and Developmental Biology, 2021
Tumor necrosis factor-associated ligand inducing apoptosis (TRAIL) induces apoptosis through the death receptors (DRs) 4 and 5 expressed on the cell surface. Upon ligand stimulation, death receptors are rapidly internalized through clathrin-dependent and
Artem A. Artykov, Anne V. Yagolovich, Anne V. Yagolovich, Dmitry A. Dolgikh, Dmitry A. Dolgikh, Mikhail P. Kirpichnikov, Mikhail P. Kirpichnikov, Daria B. Trushina, Marine E. Gasparian   +8 more
doaj   +1 more source

Biomaterials-mediated ligation of immune cell surface receptors for immunoengineering

Immuno-Oncology and Technology
A wide variety of cell surface receptors found on immune cells are essential to the body’s immunological defense mechanisms. Cell surface receptors enable immune cells to sense extracellular stimuli and identify pathogens, transmitting activating or ...
H. Cui, L. Zhang, Y. Shi
doaj   +1 more source

Signaling Pathways of Receptors Involved in Platelet Activation andShedding of These Receptors in Stored Platelets [PDF]

Advanced Pharmaceutical Bulletin, 2019
All cells encounter various signals coming from the surrounding environment and they need toreceive and respond to these signals in order to perform their functions. Cell surface receptorsare responsible for signal transduction .Platelets are blood cells
Asra Amelirad, Karim Shamsasenjan, Parvin Akbarzadehlaleh, Davoud Pashoutan Sarvar   +3 more
doaj   +1 more source

Calreticulin: Roles in Cell-Surface Protein Expression

Membranes, 2014
In order to perform their designated functions, proteins require precise subcellular localizations. For cell-surface proteins, such as receptors and channels, they are able to transduce signals only when properly targeted to the cell membrane ...
Yue Jiang, Sandeepa Dey, Hiroaki Matsunami   +2 more
doaj   +1 more source

Immunosuppressive Property of MSCs Mediated by Cell Surface Receptors

Frontiers in Immunology, 2020
In the past decade, mesenchymal stem cells (MSCs) tend to exhibit inherent tropism for refractory inflammatory diseases and engineered MSCs have appeared on the market as therapeutic agents.
Siyu Liu, Fei Liu, You Zhou, Baeku Jin, Qiang Sun, Shu Guo   +5 more
doaj   +1 more source

Cell surface receptors for CCN proteins [PDF]

Journal of Cell Communication and Signaling, 2016
The CCN family (CYR61; CTGF; NOV; CCN1-6; WISP1-3) of matricellular proteins in mammals is comprised of six homologous members that play important roles in development, inflammation, tissue repair, and a broad range of pathological processes including fibrosis and cancer.
openaire   +2 more sources

Detection of Cell Surface Dopamine Receptors [PDF]

, 2012
Dopamine receptors are a class of metabotropic G protein-coupled receptors. Plasma membrane expression is a key determinant of receptor signaling, and one that is regulated both by extra and intracellular cues. Abnormal dopamine receptor signaling is implicated in several neuropsychiatric disorders, including schizophrenia and attention deficit ...
Jiping, Xiao, Clare, Bergson
openaire   +2 more sources