Results 41 to 50 of about 1,264,389 (321)
Algebraic study of receptor-ligand systems: a dose-response analysis [PDF]
arXiv, 2022 The study of a receptor-ligand system generally relies on the analysis of its dose-response (or concentration-effect) curve, which quantifies the relation between ligand concentration and the biological effect (or cellular response) induced when binding its specific cell surface receptor.
arxiv
Immunosuppressive Property of MSCs Mediated by Cell Surface Receptors
Frontiers in Immunology, 2020 In the past decade, mesenchymal stem cells (MSCs) tend to exhibit inherent tropism for refractory inflammatory diseases and engineered MSCs have appeared on the market as therapeutic agents.
Siyu Liu +5 more
doaj +1 more source
The influence of T cell development on pathogen specificity and autoreactivity [PDF]
J. Stat. Phys. 149 (2012) 203-219, 2011 T cells orchestrate adaptive immune responses upon activation. T cell activation requires sufficiently strong binding of T cell receptors on their surface to short peptides derived from foreign proteins bound to protein products of the major histocompatibility (MHC) gene products, which are displayed on the surface of antigen presenting cells.
arxiv +1 more source
Cell surface receptors and ectoenzymes in mesangial cells. [PDF]
Journal of the American Society of Nephrology, 1992 Mesangial cells possess a variety of receptors for hormones and autacoids. They are also equipped with ectoenzymes whose function may be to control the availability of autacoids and hormones at their receptor sites. Several examples are considered. Receptors for angiotensin II (AII) are present both on murine and human mesangial cells. One single group
Raymond Ardaillou +3 more
openaire +3 more sources
Signaling Pathways of Receptors Involved in Platelet Activation andShedding of These Receptors in Stored Platelets [PDF]
Advanced Pharmaceutical Bulletin, 2019 All cells encounter various signals coming from the surrounding environment and they need toreceive and respond to these signals in order to perform their functions. Cell surface receptorsare responsible for signal transduction .Platelets are blood cells
Asra Amelirad +3 more
doaj +1 more source
Signaling receptor localization maximizes cellular information acquisition in spatially-structured, natural environments [PDF]
arXiv, 2021 Cells in natural environments like tissue or soil sense and respond to extracellular ligands with intricately structured and non-monotonic spatial distributions that are sculpted by processes such as fluid flow and substrate adhesion. Nevertheless, traditional approaches to studying cell sensing assume signals are either uniform or monotonic ...
arxiv
The trafficking and targeting of P2X receptors [PDF]
, 2013 The functional expression of P2X receptors at the plasma membrane is dependent on their trafficking along secretory and endocytic pathways. There are seven P2X receptor subunits, and these differ in their subcellular distributions because they have very ...
Murrell-Lagnado, Ruth D +1 more
core +3 more sources
Viral destruction of cell surface receptors [PDF]
Proceedings of the National Academy of Sciences, 2008 Viral infection is initiated by the attachment of the virus to the appropriate host cells. This process involves a series of dedicated virion proteins that have evolved to specifically recognize one, or a small number, of cell-surface molecules.
Andrew D. Mesecar, Kiira Ratia
openaire +2 more sources
Calreticulin: Roles in Cell-Surface Protein Expression
Membranes, 2014 In order to perform their designated functions, proteins require precise subcellular localizations. For cell-surface proteins, such as receptors and channels, they are able to transduce signals only when properly targeted to the cell membrane ...
Yue Jiang +2 more
doaj +1 more source
Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis. [PDF]
, 2017 Natural-killer receptor group 2, member D (NKG2D) is a well characterized natural killer (NK) cell activating receptor that recognizes several ligands poorly expressed on healthy cells but up-regulated upon stressing stimuli in the context of cancer or ...
Molfetta, R +3 more
core +2 more sources