Results 51 to 60 of about 1,264,389 (321)

Interaction of Viruses with Cell Surface Receptors

open access: yes, 1982
This chapter discusses the interaction of viruses with cell surface receptors. The rigorous characterizations of receptor–ligand interactions have been derived from binding studies of radiolabeled ligands in neuropharmacology and endocrinology. The definition of viral recognition sites as receptors involves three major criteria that are derived from ...
Marc Tardieu   +2 more
openaire   +3 more sources

Effect of IgG dimer concentration on the binding ability of IgG Fc fragment in IVIG to THP-1 cell surface receptors

open access: yesZhongguo shuxue zazhi, 2023
Objective To investigate the effect of immunoglobulin G (IgG) dimer concentration of intravenous immunoglobulin (IVIG) on the binding ability of IgG Fc fragment to THP-1 cell surface receptors.
Tingting LEI   +5 more
doaj   +1 more source

Immune Checkpoint Molecules in Natural Killer Cells as Potential Targets for Cancer Immunotherapy [PDF]

open access: yes, 2021
Xu et al summarizes some of the different functions of NK cells, focusing on their ability to secrete cytokines and trigger cancer cell cytotoxicity. NK cells have activating and inhibiting receptors on its cell surface, contributing to the balance of ...
Jose, Jefin
core   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Platelet Apoptosis Can Be Triggered Bypassing the Death Receptors

open access: yesClinical and Applied Thrombosis/Hemostasis, 2019
In nucleated cells, the extrinsic pathway of the programmed cell death (apoptosis) is triggered by interaction of death ligands of the tumor necrosis factor superfamily with the death receptors on external cell surface membrane.
Valery Leytin PhD   +2 more
doaj   +1 more source

Interplay Between Receptor-Ligand Binding and Lipid Domain Formation Depends on the Mobility of Ligands in Cell-Substrate Adhesion

open access: yesFrontiers in Molecular Biosciences, 2021
Cell-cell adhesion and the adhesion of cells to extracellular matrix are mediated by the specific binding of receptors on the cell membrane to their cognate ligands on the opposing surface.
Long Li   +7 more
doaj   +1 more source

A Thermodynamic Model for Receptor Clustering [PDF]

open access: yes, 1999
Intracellular signaling often arises from ligand-induced oligomerization of cell surface receptors. This oligomerization or clustering process is fundamentally a cooperative behavior between near-neighbor receptor molecules; the properties of this cooperative process clearly affects the signal transduction.
arxiv   +1 more source

Dynamics of Natural Killer cell receptor revealed by quantitative analysis of photoswitchable protein [PDF]

open access: yesBiophysical Journal, Volume 105, 1-10, (2013), 2013
Natural Killer (NK) cell activation is dynamically regulated by numerous activating and inhibitory surface receptors that accumulate at the immune synapse. Quantitative analysis of receptor dynamics has been limited by methodologies which rely on indirect measurements such as fluorescence recovery after photobleaching.
arxiv   +1 more source

New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]

open access: yes, 1975
New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J.   +3 more
core   +2 more sources

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