The role of dimerisation in the cellular trafficking of G-protein-coupled receptors [PDF]
The concept that G-protein-coupled receptors can exist as homomeric and/or heteromeric complexes is now well established. Despite this, how dynamic such interactions are and if this may be modulated during receptor trafficking remain topics of debate ...
Milligan, Graeme
core +1 more source
Unraveling nanotopography of cell surface receptors [PDF]
ABSTRACTCells communicate with their environment via surface receptors, but nanoscopic receptor organization with respect to complex cell surface morphology remains unclear. This is mainly due to a lack of accessible, robust and high-resolution methods.
Franke, Christian +9 more
openaire +4 more sources
Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis [PDF]
Superparamagnetic iron oxide nanoparticles have been used for many years as magnetic resonance imaging contrast agents or in drug delivery applications.
Berry, C.C. +3 more
core +1 more source
Multispecific lymphoid cell surface receptors. [PDF]
When mice are sequentially immunized with two antigens to give an oligoclonal "double-binding" antibody response, there is a concomitant increase of "double-binding" cell surface receptors on their splenic lymphocytes. Competition studies suggest that the capacity to bind the two ligands, bovine pancreatic ribonuclease (EC 3.1.4.22) and a 2,4 ...
Frank F. Richards +2 more
openaire +3 more sources
The activating receptors 2B4 and NTB-A, but not CRACC are subject to ligand-induced down-regulation on human natural killer cells [PDF]
Activation of natural killer cells can be mediated by different receptors. Stimulation of the receptors 2B4, NTB-A and CRACC, members of the SLAM-related receptor family, induces cytotoxicity and cytokine production.
Carolin Böhm +4 more
core +2 more sources
Cell-cell adhesion and the adhesion of cells to extracellular matrix are mediated by the specific binding of receptors on the cell membrane to their cognate ligands on the opposing surface.
Long Li +7 more
doaj +1 more source
Expression of interleukin 2 receptors on activated human B cells. [PDF]
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF +8 more
core
The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]
G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin +8 more
core +2 more sources
Role of Glycans on Key Cell Surface Receptors That Regulate Cell Proliferation and Cell Death
Cells undergo proliferation and apoptosis, migration and differentiation via a number of cell surface receptors, most of which are heavily glycosylated.
Yin Gao +3 more
doaj +1 more source
Cell receptor-independent infection by a neurotropic murine coronavirus. [PDF]
The cellular receptors for a coronavirus, mouse hepatitis virus (MHV), have been recently identified as one or more members of the carcinoembryonic antigen (CEA) family. The neurotropic JHM strain of MHV (MHV-JHM) possesses a highly fusogenic surface (S)
Buchmeier, MJ, Gallagher, TM, Perlman, S
core

