Results 81 to 90 of about 1,161,650 (208)

Fetal-derived trophoblast use the apoptotic cytokine tumor necrosis factor-alpha-related apoptosis-inducing ligand to induce smooth muscle cell death. [PDF]

open access: yes, 2007
Remodeling of the uterine spiral arteries during pregnancy transforms them from high to low resistance vessels that lack vasoconstrictive properties. This process is essential to meet the demand for increased blood flow imposed by the growing fetus. Loss
Aplin, JD   +6 more
core   +1 more source

Analyzing the Role of Receptor Internalization in the Regulation of Melanin-Concentrating Hormone Signaling

open access: yesInternational Journal of Endocrinology, 2013
The regulation of appetite is complex, though our understanding of the process is improving. The potential role for the melanin-concentrating hormone (MCH) signaling pathway in the treatment of obesity is being explored by many.
Jay I. Moden   +4 more
doaj   +1 more source

Cell Receptors for Influenza A Viruses and the Innate Immune Response

open access: yesFrontiers in Microbiology, 2012
The interaction of the hemagglutinin (HA) of the influenza A viruses (IAV) with the cell surface is a key factor for entry of the virus and productive infection of the cell.
Irene eRamos, Ana eFernandez-Sesma
doaj   +1 more source

Increased accuracy of ligand sensing by receptor internalization

open access: yes, 2010
Many types of cells can sense external ligand concentrations with cell-surface receptors at extremely high accuracy. Interestingly, ligand-bound receptors are often internalized, a process also known as receptor-mediated endocytosis.
A. Levitzki   +12 more
core   +1 more source

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. [PDF]

open access: yes, 1991
We investigated the role of the integrins alpha v beta 3 and alpha v beta 5 in mediating vitronectin adhesion of three phenotypically distinct cell types.
Cheresh, DA, Orlando, RA, Wayner, EA
core  

NKp44 and Natural Cytotoxicity Receptors as Damage Associated Molecular Pattern Recognition Receptors

open access: yesFrontiers in Immunology, 2015
Natural Killer (NK) cells are a key constituent of the innate immune system, protecting against bacteria, virally infected cells, and cancer. Recognition and protective function against such cells is dictated by activating and inhibitory receptors on ...
Porunelloor Abraham Mathew   +1 more
doaj   +1 more source

A natural killer cell receptor specific for a major histocompatibility complex class I molecule. [PDF]

open access: yes, 1994
Target cell expression of major histocompatibility complex (MHC) class I molecules correlates with resistance to lysis by natural killer (NK) cells.
Daniels, BF   +3 more
core  

Innate Immunity and Cell Surface Receptors in the Pathogenesis of COPD: Insights from Mouse Smoking Models

open access: yesInternational Journal of COPD, 2020
Giovanna De Cunto, Eleonora Cavarra, Barbara Bartalesi, Monica Lucattelli, Giuseppe Lungarella Department of Molecular and Developmental Medicine, University of Siena, Siena, ItalyCorrespondence: Giuseppe Lungarella Email lungarella.giuseppe@gmail ...
De Cunto G   +4 more
doaj  

Thematic review series: The Immune System and Atherogenesis. Recent insights into the biology of macrophage scavenger receptors

open access: yesJournal of Lipid Research, 2005
Scavenger receptors were originally defined by their ability to bind and internalize modified lipoproteins. Macrophages express at least six structurally different cell surface receptors for modified forms of LDL that contribute to foam cell formation in
David R. Greaves, Siamon Gordon
doaj   +1 more source

Morphogen Transport in Epithelia

open access: yes, 2006
We present a general theoretical framework to discuss mechanisms of morphogen transport and gradient formation in a cell layer. Trafficking events on the cellular scale lead to transport on larger scales. We discuss in particular the case of transcytosis
B. Houchmandzadeh   +8 more
core   +1 more source

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