Results 81 to 90 of about 2,926,869 (253)

Redistribution of cell surface receptors induced by cell-cell contact

Journal of Cell Biology, 1982
Cell surface lectin receptors underwent rapid redistribution after embryonic Xenopus myotomal muscle cells were manipulated into contact in culture. Soybean agglutinin (SBA) receptors became highly concentrated at the contact area and concanavalin A (Con
I. Chow, M. Poo
semanticscholar   +1 more source

Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension

eLife, 2015
Cell surface receptors are central to the cell's ability to generate coordinated responses to the multitude of biochemical and physical cues in the microenvironment.
Joanna P Rys, Christopher C DuFort, David A Monteiro, Michelle A Baird, Juan A Oses-Prieto, Shreya Chand, Alma L Burlingame, Michael W Davidson, Tamara N Alliston   +8 more
doaj   +1 more source

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells [PDF]

, 2007
Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8+ T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide–major
Allen, R, Allen, TM, Allgaier, R, Altfeld, M, Feeney, M, Gandhi, RT, Kavanagh, DG, Lichterfeld, M, Miura, T, Moza, B, Mui, SK, Pereyra, F, Rosenberg, ES, Sivamurthy, R, Sundberg, EJ, Trocha, A, Walker, BD, Williams, KL, Yu, XG   +18 more
core   +3 more sources

Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans

Journal of Cell Biology, 1992
The role of cell surface heparan sulfate in herpes simplex virus (HSV) infection was investigated using CHO cell mutants defective in various aspects of glycosaminoglycan synthesis.
M. Shieh, D. WuDunn, R. Montgomery, J. Esko, P. Spear   +4 more
semanticscholar   +1 more source

An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism [PDF]

, 2018
Cholesterol regulation is an important aspect of human health. In this work we bring together and extend two recent mathematical models describing cholesterol biosynthesis and lipoprotein endocytosis to create an integrated model of lipoprotein ...
Pool, Frances, Sweby, Peter K., Tindall, Marcus J.   +2 more
core   +2 more sources

Heterogeneity of cell surface endothelin receptors.

Journal of Biological Chemistry, 1990
Two distinct cell surface endothelin receptors were identified, namely a 73-kDa protein referred to as ET-R1 and a 60-kDa protein named ET-R2. ET-R1 was expressed as the sole endothelin receptor on rat A10 vascular smooth muscle cells and C6 glial cells.
E R Martin, Barry M. Brenner, Barbara J. Ballermann   +2 more
openaire   +2 more sources

SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons

Neuroscience Research
Long-term depression (LTD) is a form of synaptic plasticity thought to be the cellular basis of experience-dependent learning and memory. LTD is caused by an activity-dependent decrease in cell surface α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Misaki Morishita, Shinji Matsuda
doaj   +1 more source

P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]

, 2008
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King, Bucheimer RE, Dai LJ, Dubyak GR, Egan TM, Inscho EW, King BF, Lazarowski ER, Lazarowski ER, Lehrmann H, Leipziger J, Li L, McCoy DE, North RA, Pelegrin P, Piper AS, Ralevic V, Schwiebert EM, Scott S.P. Wildman, Shirley DG, Taylor AL, Unwin RJ, Vekaria R, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wolff SC, Zhang Y   +29 more
core   +1 more source

Sugar Free: Novel Immunotherapeutic Approaches Targeting Siglecs and Sialic Acids to Enhance Natural Killer Cell Cytotoxicity Against Cancer

Frontiers in Immunology, 2019
Natural Killer (NK) cells are cytotoxic lymphocytes that play a key role in the immune system, targeting and destroying invading pathogens and malignantly transformed cells.
John Daly, Mattias Carlsten, Michael O'Dwyer   +2 more
doaj   +1 more source

Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth. [PDF]

, 1987
Neuronal responses to extracellular matrix (ECM) constituents are likely to play an important role in nervous system development and regeneration. We have studied the interactions of a neuron-like rat pheochromocytoma cell line, PC12, with ECM protein ...
Damsky, CH, Reichardt, LF, Tomaselli, KJ
core