Results 101 to 110 of about 2,443,583 (255)

Antinociceptive Activity of Methanolic Extract of Clinacanthus nutans Leaves: Possible Mechanisms of Action Involved

open access: yesPain Research and Management, 2018
Methanolic extract of Clinacanthus nutans Lindau leaves (MECN) has been proven to possess antinociceptive activity that works via the opioid and NO-dependent/cGMP-independent pathways.
Zainul Amiruddin Zakaria   +8 more
doaj   +1 more source

Selectively driving cholinergic fibers optically in the thalamic reticular nucleus promotes sleep

open access: yeseLife, 2016
Cholinergic projections from the basal forebrain and brainstem are thought to play important roles in rapid eye movement (REM) sleep and arousal. Using transgenic mice in which channelrhdopsin-2 is selectively expressed in cholinergic neurons, we show ...
Kun-Ming Ni   +9 more
doaj   +1 more source

Muscarinic cholinergic receptors in rabbit retina

open access: yesJournal of Pharmacy and Pharmacology, 1985
Abstract Binding sites with high affinity and specificity for [3 H]-quinuclidinyl benzilate are present in rabbit retinal homogenates. Only one set of binding sites was detected with an apparent dissociation constant of 2.13 times 10−10 M and a density of 59.2 fmol mg−1 of protein.
M J Neal, C Dawson
openaire   +3 more sources

Cholinergic Axons Modulate GABAergic Signaling among Hippocampal Interneurons via Postsynaptic α7 Nicotinic Receptors

open access: yesJournal of Neuroscience, 2007
Homopentameric α7 nicotinic receptors have a high affinity for acetylcholine (ACh), are permeable to Ca2+ ions, and are abundant in hippocampal interneurons.
N. Wanaverbecq   +4 more
semanticscholar   +1 more source

Autoradiographic localization of muscarinic cholinergic receptors in rat brainstem

open access: yesJournal of Neuroscience, 1981
We have localized muscarinic cholinergic receptors in the rat brainstem by a light microscopic autoradiographic method. Initially, we examined the kinetics and specificity of the binding of radiolabeled quinuclidinyl benzilate ([3H]QNB) in slide-mounted,
J. Wamsley   +3 more
semanticscholar   +1 more source

Meta-Potentiation: Neuro-Astroglial Interactions Supporting Perceptual Consciousness [PDF]

open access: yes, 2007
Conscious perceptual processing involves the sequential activation of cortical networks at several brain locations, and the onset of oscillatory synchrony affecting the same neuronal population.
Alfredo Pereira Jr, Fá
core   +2 more sources

Acetylcholine in irritable bowel syndrome pathogenesis and the role of cholineblockers

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011
The aim of review. To demonstrate value of disorders of cholinergic innervation in pathogenesis of irritable bowel syndrome (IBS).Original positions. The important place in regulation of gastro-intestinal tract functions belongs not only to M-, but also ...
Yu. O. Shulpekova
doaj  

GABA_{B} Receptors Regulate Chick Retinal Calcium Waves [PDF]

open access: yes, 2001
Correlated spiking activity and associated Ca²⁺ waves in the developing retina are important in determining the connectivity of the visual system. Here, we show that GABA, via GABA_{B} receptors, regulates the temporal characteristics of Ca²⁺ waves ...
Catsicas, M, Mobbs, P
core  

Subtle changes in striatal muscarinic M1 and M4 receptor expression in the DYT1 knock-in mouse model of dystonia.

open access: yesPLoS ONE, 2019
In early-onset generalized torsion dystonia, caused by a GAG deletion in TOR1A (DYT1), enhanced striatal cholinergic activity has been suggested to be critically involved. Previous studies have shown increased acetylcholine levels in the striatum of DYT1
Franziska Richter   +3 more
doaj   +1 more source

Distribution of α7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse. [PDF]

open access: yes, 2019
Homomeric α7 nicotinic acetylcholine receptors (nAChRs) are abundantly expressed in the central and peripheral nervous system (CNS and PNS, respectively), and spinal cord.
Broide, Ron S   +3 more
core   +1 more source

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