Results 51 to 60 of about 2,408,414 (357)

Punica granatum peel supplementation attenuates cognitive deficits and brain injury in rat by targeting the Nrf2‐HO‐1 pathway

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 168-180, January 2023., 2023
The hydro‐ethanolic extract of P. granatum peel was standardized. ;The extract increased superoxide dismutase activity and thiol content, while reduced function of AchE and peroxidation of lipid in the scopolamine‐injured rat’s brain. ;P. granatum may attenuate scopolamine injury through targeting nuclear factor‐E2‐related factor 2 pathway ; Abstract ...
Mahsan Akbarian   +5 more
wiley   +1 more source

Using ResNet to Utilize 4-class T2-FLAIR Slice Classification Based on the Cholinergic Pathways Hyperintensities Scale for Pathological Aging [PDF]

open access: yesarXiv, 2023
The Cholinergic Pathways Hyperintensities Scale (CHIPS) is a visual rating scale used to assess the extent of cholinergic white matter hyperintensities in T2-FLAIR images, serving as an indicator of dementia severity. However, the manual selection of four specific slices for rating throughout the entire brain is a time-consuming process.
arxiv  

Cooperative Glutamatergic and Cholinergic Mechanisms Generate Short-Term Modifications of Synaptic Effectiveness in Prepositus Hypoglossi Neurons [PDF]

open access: yes, 2005
To maintain horizontal eye position on a visual target after a saccade, extraocular motoneurons need a persistent (tonic) neural activity, called "eye-position signal," generated by prepositus hypoglossi (PH) neurons.
Delgado-Garcia, JM   +2 more
core   +1 more source

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]

open access: yes, 2014
The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard   +4 more
core   +7 more sources

Dopamine and Serotonin-Induced Modulation of GABAergic and Glutamatergic Transmission in the Striatum and Basal Forebrain

open access: yesFrontiers in Neuroanatomy, 2017
Catecholamine receptor-mediated modulation of glutamatergic or GABAergic transmission in the striatum as well as basal forebrain (BF) has been intensively studied during these two decades.
Toshihiko Momiyama, Takuma Nishijo
doaj   +1 more source

Plasticity in ventral pallidal cholinergic neuron-derived circuits contributes to comorbid chronic pain-like and depression-like behaviour in male mice

open access: yesNature Communications, 2023
Nucleus- and cell-specific interrogation of individual basal forebrain (BF) cholinergic circuits is crucial for refining targets to treat comorbid chronic pain-like and depression-like behaviour.
Ya-Wei Ji   +12 more
doaj   +1 more source

Axonal α7* nicotinic acetylcholine receptors modulate glutamatergic signaling and synaptic vesicle organization in ventral hippocampal projections

open access: yesFrontiers in Neural Circuits, 2022
Modulation of the release of glutamate by activation of presynaptic nicotinic acetylcholine receptors (nAChRs) is one of the most prevalent mechanism of nicotinic facilitation of glutamatergic transmission in cortico-limbic circuits.
Chongbo Zhong   +3 more
doaj   +1 more source

Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts [PDF]

open access: yes, 2019
Biological membranes show lateral and transverse asymmetric lipid distribution. Cholesterol (Chol) localizes in both hemilayers, but in the external one it is mostly condensed in lipid-ordered microdomains (raft domains), together with saturated ...
Antollini, Silvia Susana   +1 more
core   +1 more source

Modulation of Hippocampal Circuits by Muscarinic and Nicotinic Receptors

open access: yesFrontiers in Neural Circuits, 2017
This article provides a review of the effects of activation of muscarinic and nicotinic receptors on the physiological properties of circuits in the hippocampal formation.
Holger Dannenberg   +2 more
doaj   +1 more source

Central Cholinergic Nervous System and Cholinergic Agents

open access: yesActa Medica, 1998
Central cholinergic nervous system play important role in many physiological and behavioral functions in humans. The activity of the cholinergic nervous system depends upon the production and fate of acetylcholine and all compounds influenced its ...
Jiří Patočka
doaj   +1 more source

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