Results 81 to 90 of about 141,106 (207)

Muscarinic modulation of M and h currents in gerbil spherical bushy cells.

open access: yesPLoS ONE, 2020
Descending cholinergic fibers innervate the cochlear nucleus. Spherical bushy cells, principal neurons of the anterior part of the ventral cochlear nucleus, are depolarized by cholinergic agonists on two different time scales.
Charlène Gillet   +2 more
doaj   +1 more source

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats [PDF]

open access: yes, 2017
Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in
A Bari   +36 more
core   +2 more sources

Cholinergic modulation of hippocampal network function

open access: yesFrontiers in Synaptic Neuroscience, 2013
Cholinergic septohippocampal projections from the medial septal area to the hippocampus are proposed to have important roles in cognition by modulating properties of the hippocampal network.
Leonor eTeles-Grilo Ruivo, Jack eMellor
doaj   +1 more source

Antinociceptive Activity of Methanolic Extract of Clinacanthus nutans Leaves: Possible Mechanisms of Action Involved

open access: yesPain Research and Management, 2018
Methanolic extract of Clinacanthus nutans Lindau leaves (MECN) has been proven to possess antinociceptive activity that works via the opioid and NO-dependent/cGMP-independent pathways.
Zainul Amiruddin Zakaria   +8 more
doaj   +1 more source

A Local Circuit Model of Learned Striatal and Dopamine Cell Responses under Probabilistic Schedules of Reward [PDF]

open access: yes, 2007
Before choosing, it helps to know both the expected value signaled by a predictive cue and the associated uncertainty that the reward will be forthcoming. Recently, Fiorillo et al.
Bullock, Daniel, Tan, Can Ozan
core   +1 more source

Chronic Nicotine Selectively Enhances α4β2* Nicotinic Acetylcholine Receptors in the Nigrostriatal Dopamine Pathway [PDF]

open access: yes, 2009
These electrophysiological experiments, in slices and intact animals, study the effects of in vivo chronic exposure to nicotine on functional α4β2* nAChRs in the nigrostriatal dopaminergic (DA) pathway.
Cai, Haijiang   +5 more
core  

Muscarinic cholinergic receptors in rabbit retina

open access: yesJournal of Pharmacy and Pharmacology, 1985
Abstract Binding sites with high affinity and specificity for [3 H]-quinuclidinyl benzilate are present in rabbit retinal homogenates. Only one set of binding sites was detected with an apparent dissociation constant of 2.13 times 10−10 M and a density of 59.2 fmol mg−1 of protein.
M J, Neal, C, Dawson
openaire   +2 more sources

Selectively driving cholinergic fibers optically in the thalamic reticular nucleus promotes sleep

open access: yeseLife, 2016
Cholinergic projections from the basal forebrain and brainstem are thought to play important roles in rapid eye movement (REM) sleep and arousal. Using transgenic mice in which channelrhdopsin-2 is selectively expressed in cholinergic neurons, we show ...
Kun-Ming Ni   +9 more
doaj   +1 more source

Biological Functions of Keratinocyte Cholinergic Receptors

open access: yesJournal of Investigative Dermatology Symposium Proceedings, 1997
Human epidermal keratinocytes possess cholinergic enzymes, which synthesize and degrade acetylcholine, and express both nicotinic and muscarinic classes of cholinergic receptors on their cell surfaces. These receptors bind acetylcholine and initiate cellular response.
openaire   +2 more sources

Acetylcholine in irritable bowel syndrome pathogenesis and the role of cholineblockers

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011
The aim of review. To demonstrate value of disorders of cholinergic innervation in pathogenesis of irritable bowel syndrome (IBS).Original positions. The important place in regulation of gastro-intestinal tract functions belongs not only to M-, but also ...
Yu. O. Shulpekova
doaj  

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