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Transcriptional Profile Change of NK-92 Cells in Presence of Cytokines, TGFβ Signaling Pathway Inhibitor and CDK7/12/13 Kinase Inhibitor. [PDF]
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Biological functions and therapeutic opportunities of soluble cytokine receptors.
Cytokine & growth factor reviews, 2020Cytokines control the immune system by regulating the proliferation, differentiation and function of immune cells. They activate their target cells through binding to specific receptors, which either are transmembrane proteins or attached to the cell ...
J. Lokau, Christoph Garbers
semanticscholar +1 more source
2016
Cytokine receptors initiate intracellular signalling that regulate a diverse range of biological and medically important functions including metabolism control, neural stem cell activation, inflammatory responses, bone development, as well as blood cell and immune cell development and growth.
Brooks, Andrew J. +2 more
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Cytokine receptors initiate intracellular signalling that regulate a diverse range of biological and medically important functions including metabolism control, neural stem cell activation, inflammatory responses, bone development, as well as blood cell and immune cell development and growth.
Brooks, Andrew J. +2 more
openaire +4 more sources
Cytokines, receptors, and inhibitors
The Clinical Investigator, 1992Cytokines are endogenous mediators in inflammatory and immunologic host defense reactions. In various diseases cytokines produced in excess cause systemic or local toxic effects. Cytokines therefore are tightly controlled by regulation of their biosynthesis and release and by counteracting mechanisms which limit their activities.
G, Gehr, T, Braun, W, Lesslauer
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Cytokines and their receptors in transplantation
Current Opinion in Immunology, 1991Abstract In this review we will discuss cytokine expression within organ transplants, the measurement of cytokines and their receptors as a tool for monitoring graft rejection, cytokines and their receptors as targets of immunosuppression and new directions of this research in transplantation.
M J, Dallman, G J, Clark
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The cytokine receptor superfamily
Blood Reviews, 1991The binding of haemopoietic growth factors and cytokines to specific receptors triggers a cascade of intracellular events which results in cell proliferation and differentiation. The knowledge of ligand-receptor-signal pathways is not only important in understanding the pathophysiology of malignant disease but also essential for devising future ...
R S, Kaczmarski, G J, Mufti
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Current Opinion in Immunology, 1991
The molecular characterization of cytokine receptors has progressed rapidly over the past 5 years as a result of availability of radiolabeled cytokines, as well as the identification or creation of cell lines that express significant numbers of receptors at the cell surface.
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The molecular characterization of cytokine receptors has progressed rapidly over the past 5 years as a result of availability of radiolabeled cytokines, as well as the identification or creation of cell lines that express significant numbers of receptors at the cell surface.
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Journal of Clinical Immunology, 1990
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
S K, Dower, C A, Smith, L S, Park
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Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
S K, Dower, C A, Smith, L S, Park
openaire +2 more sources