Results 251 to 260 of about 1,196,650 (308)
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Journal of Clinical Immunology, 1990
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
S K, Dower, C A, Smith, L S, Park
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Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
S K, Dower, C A, Smith, L S, Park
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Cytokines, receptors, and inhibitors
The Clinical Investigator, 1992Cytokines are endogenous mediators in inflammatory and immunologic host defense reactions. In various diseases cytokines produced in excess cause systemic or local toxic effects. Cytokines therefore are tightly controlled by regulation of their biosynthesis and release and by counteracting mechanisms which limit their activities.
G, Gehr, T, Braun, W, Lesslauer
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Cytokines and their receptors in transplantation
Current Opinion in Immunology, 1991Abstract In this review we will discuss cytokine expression within organ transplants, the measurement of cytokines and their receptors as a tool for monitoring graft rejection, cytokines and their receptors as targets of immunosuppression and new directions of this research in transplantation.
M J, Dallman, G J, Clark
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Trends in Endocrinology & Metabolism, 1994
Cytokines are pleiotropic regulators that control proliferation, differentiation, and other cellular functions. They play a pivotal role in the immune and hematopoietic systems, and subsets of cytokines often exhibit similar biologic activities in common target cells. Recent cloning of genes for the cytokine receptors has provided new insights into the
T, Kitamura, T, Ogorochi, A, Miyajima
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Cytokines are pleiotropic regulators that control proliferation, differentiation, and other cellular functions. They play a pivotal role in the immune and hematopoietic systems, and subsets of cytokines often exhibit similar biologic activities in common target cells. Recent cloning of genes for the cytokine receptors has provided new insights into the
T, Kitamura, T, Ogorochi, A, Miyajima
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Keratinocyte Cytokine and Chemokine Receptors
Dermatologic Clinics, 2007Chemokines are a superfamily of small, secreted proteins that regulate cell traffic in homeostatic and inflammatory conditions. Keratinocytes synthesize many chemokines, including members of the CC and CXC subfamilies, such as regulated on activation of normal T-cell expressed and secreted, gamma-interferon inducible protein-10, monokine induced by ...
Tuezuen, Yalcin +3 more
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Cytokine Receptors of the Lung
American Journal of Respiratory Cell and Molecular Biology, 1991Abstract There has been a dramatic increase in studies on the potential role of cytokines in controlling the processes of inflammation, injury, and repair in the lung. A vast array or network has emerged including all of the cells that produce the various cytokines that have been identified and the target cells that respond to these ...
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Cytokine-Cytokine Receptor Structure
Science's STKE, 2005Interleukin-2 (IL-2) is central to the immune response. It forms a complex with three cell surface receptors, IL-2Rα, IL-2Rβ, and IL-2Rγ, to form a complex that signals through activation of downstream tyrosine kinases, JAK3 and STAT. Rickert et al.
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Nature, 1995
Many cell functions are regulated by members of the cytokine receptor superfamily. Signalling by these receptors depends upon their association with Janus kinases (JAKs), which couple ligand binding to tyrosine phosphorylation of signalling proteins recruited to the receptor complex.
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Many cell functions are regulated by members of the cytokine receptor superfamily. Signalling by these receptors depends upon their association with Janus kinases (JAKs), which couple ligand binding to tyrosine phosphorylation of signalling proteins recruited to the receptor complex.
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Cytokine Receptors: A New Superfamily of Receptors
1993Publisher Summary This chapter discusses the characteristics that define the structure and composition of the receptors and their ability to bind ligand and transduce signals, known as “signal transduction pathways,” and provides the evidence for oncogenic processes dependent on aberrant cytokine–receptor interactions.
J, Schreurs, D M, Gorman, A, Miyajima
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