MGPT: A Multi‐task Graph Prompt Learning Framework for Drug Discovery
MGPT is a unified multi‐task graph prompt learning model providing generalizable and robust graph representations for few‐shot drug association prediction. MGPT demonstrates the ability of seamless task switching and outperforms competitive approaches in few‐shot scenarios.
Yang Li+4 more
wiley +1 more source
The manicogenic properties of clozapine: a rare but serious potential adverse effect. [PDF]
Cholette-Tétrault S+3 more
europepmc +1 more source
Magnetically Controllable and Degradable Milliscale Swimmers as Intraocular Drug Implants
Magnetically controllable degradable milliscale swimmers (MDMS) offer a promising alternative to commercial intraocular drug implants, reducing complications like implant dislocation and uncontrolled drug release. MDMS achieve high velocities in ocular environments, enable real‐time imaging, and deliver drugs effectively without disrupting retinal ...
Erdost Yildiz+8 more
wiley +1 more source
Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine-endocannabinoid mechanism relevant to migraine. [PDF]
Christiansen IM+4 more
europepmc +1 more source
Inspired by mussel nacre and byssus, a multi‐type dynamic chemically bonded epoxy/MXene adaptable network is fabricated through a hierarchical assembly strategy, establishing the toughest (210.75 MJ m−3) room‐temperature self‐healing (90.04% recovery within 2 h at 25 °C) epoxy resin to date, challenging the limitations of conventional thermosetting ...
Xiaobo Zhu+4 more
wiley +1 more source
Differential Effects of Prenatal Poly I:C Exposure and Antipsychotics on NMDA/GABA Receptors and GSK3β-Mediated Signaling in the Dorsal Raphe Nucleus of Female Rats. [PDF]
Chen S, Lian J, Su Y, Deng C.
europepmc +1 more source
The rising demand for efficient energy systems has spotlighted 2D mesoporous carbon materials due to their high surface area, tunable porosity, and electrical conductivity. This article explores synthesis methods (template‐assisted, chemical vapor deposition), fabrication techniques (electrospinning, freeze‐drying), and applications in batteries ...
Pariksha Bishnoi+5 more
wiley +1 more source
A temporally restricted function of the dopamine receptor Dop1R2 during memory formation. [PDF]
Kaldun JC+5 more
europepmc +1 more source
On apomorphine and dopamine receptors
Geoffrey N. Woodruff+2 more
openaire +3 more sources
The presented work introduces a novel type of covalently bonded nanomagnet‐based hydrogel composite, which comprises exchange‐coupled iron platinum‐zinc‐ferrite nanoparticles for tunable magnetic manipulation. This composite exhibits high stability and biocompatibility, making it a promising material for advancing magnetic microrobotic applications in ...
Lukas Hertle+15 more
wiley +1 more source