Results 171 to 180 of about 2,841 (216)
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Dopamine receptor agonists: selectivity and dopamine D1 receptor efficacy
European Journal of Pharmacology: Molecular Pharmacology, 1990Dopamine receptor selectivity was investigated for a number of dopamine receptor agonists. In vitro, the benzazepine derivatives, e.g., SKF 38393 and SKF 75670 as well as the isoquinoline derivatives, SKF 89626 and SKF 89615, were D1 receptor-selective. All other compounds like apomorphine, CY 208-243, 6,7-ADTN and 3-PPP were either D2-selective or did
P H, Andersen, J A, Jansen
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Schizophrenia and dopamine receptors
European Neuropsychopharmacology, 2013Schizophrenia patients are behaviorally supersensitive to dopamine-like drugs such as amphetamine or methylphenidate, meaning that patients respond to such drugs with increased psychotic symptoms, as compared to control subjects. A basis of such supersensitivity may be an increased pre-synaptic release of dopamine or a post-synaptic elevation of D2 ...
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2001
Publisher Summary This chapter provides an overview of the role of the Dl-like dopamine receptors in nervous system function. The goal is to provide a broader, integrated overview that relates the structure and function of these interesting receptors to how the D1 receptors may interact with human neurological and psychiatric diseases. The peripheral
X, Huang +4 more
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Publisher Summary This chapter provides an overview of the role of the Dl-like dopamine receptors in nervous system function. The goal is to provide a broader, integrated overview that relates the structure and function of these interesting receptors to how the D1 receptors may interact with human neurological and psychiatric diseases. The peripheral
X, Huang +4 more
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American Journal of Hypertension, 1990
Since 1979 when two subtypes of peripheral dopamine receptors (DA1 and DA2) were first proposed, much progress has been made to confirm such a view. Cumulative experience with the dog in vivo models suggests that the potency order: fenoldopam greater than dopamine greater than dipropyl dopamine greater than apomorphine characterizes the DA1 receptor ...
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Since 1979 when two subtypes of peripheral dopamine receptors (DA1 and DA2) were first proposed, much progress has been made to confirm such a view. Cumulative experience with the dog in vivo models suggests that the potency order: fenoldopam greater than dopamine greater than dipropyl dopamine greater than apomorphine characterizes the DA1 receptor ...
openaire +2 more sources
2002
Abstract Dopamine is one of the major neurotransmitters in the central nervous system. Central dopaminergic systems participate in a number of important physiological functions. These systems control voluntary as well as involuntary motor movements, execution of learned motor programs, and regulate the secretion of prolactin and ...
Lucien Gazi, Philip G Strange
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Abstract Dopamine is one of the major neurotransmitters in the central nervous system. Central dopaminergic systems participate in a number of important physiological functions. These systems control voluntary as well as involuntary motor movements, execution of learned motor programs, and regulate the secretion of prolactin and ...
Lucien Gazi, Philip G Strange
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Wave-like dopamine dynamics as a mechanism for spatiotemporal credit assignment
Cell, 2021Arif A Hamid +2 more
exaly
Neostriatal dopamine receptors
Trends in Neurosciences, 1990De Keyser, Jacques, Ebinger, Guy
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Dopamine receptors and schizophrenia
Biochemical Society Transactions, 1996openaire +2 more sources