Results 31 to 40 of about 673,565 (253)

Tetrahydrocannabinol and Dopamine D1 Receptor [PDF]

open access: yes, 2023
Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family. The D1
Jiwon, Lee
core   +1 more source

M₅ muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. [PDF]

open access: yesPLoS ONE, 2011
Opiates, like other addictive drugs, elevate forebrain dopamine levels and are thought to do so mainly by inhibiting GABA neurons near the ventral tegmental area (VTA), in turn leading to a disinhibition of dopamine neurons.
Stephan Steidl   +3 more
doaj   +1 more source

Modulation of Neuron and Astrocyte Dopamine Receptors via Receptor–Receptor Interactions

open access: yesPharmaceuticals, 2023
Dopamine neurotransmission plays critical roles in regulating complex cognitive and behavioral processes including reward, motivation, reinforcement learning, and movement.
Diego Guidolin   +6 more
doaj   +1 more source

Dopamine Receptors and Neurodegeneration [PDF]

open access: yesAging and disease, 2015
Dopamine (DA) is one of the major neurotransmitters and participates in a number of functions such as motor coordination, emotions, memory, reward mechanism, neuroendocrine regulation etc. DA exerts its effects through five DA receptors that are subdivided in 2 families: D1-like DA receptors (D1 and D5) and the D2-like (D2, D3 and D4). All DA receptors
Claudia, Rangel-Barajas   +2 more
openaire   +2 more sources

Cardiovascular Dopamine Receptors: Role of Renal Dopamine and Dopamine Receptors in Sodium Excretion [PDF]

open access: yesPharmacology & Toxicology, 1990
Research efforts in the area of peripheral dopamine have now established the presence of two distinct subtypes--DA1 and DA2--of DA receptors, and have identified a potential role for dopamine produced within the kidney in the control of renal sodium excretion.
M F, Lokhandwala, S S, Hegde
openaire   +2 more sources

Physiological and Functional Basis of Dopamine Receptors and Their Role in Neurogenesis: Possible Implication for Parkinson’s disease

open access: yesJournal of Experimental Neuroscience, 2018
Dopamine controls various physiological functions in the brain and periphery by acting on its receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors involved in the regulation of motor activity and several neurological ...
Akanksha Mishra   +2 more
doaj   +1 more source

Purkinje cell dopaminergic inputs to astrocytes regulate cerebellar-dependent behavior

open access: yesNature Communications, 2023
The role of dopamine in the cerebellum remains relatively unexplored. Here, the authors report a dopamine system in the cerebellum in mice, where Purkinje cells supply dopamine and Bergmann glia express D1 receptors.
Chang Li   +7 more
doaj   +1 more source

D2-Like Receptors Mediate Dopamine-Inhibited Insulin Secretion via Ion Channels in Rat Pancreatic β-Cells

open access: yesFrontiers in Endocrinology, 2020
Dopamine (DA) has a vital role in the central nervous system and also modulates lipid and glucose metabolism. The present study aimed to investigate the effect of dopamine on insulin secretion and the underlying mechanisms in rat pancreatic β-cells. Data
Mengmeng Liu   +15 more
doaj   +1 more source

Conformation of dopamine at the dopamine receptor. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1978
Tritiated dopamine was used to label the dopamine receptor in membranes isolated from the rat corpus striatum. Scatchard analysis of displacement of [3H]dopamine by nonradioactive dopamine indicated the presence of two binding sites. The similarities in affinity, capacity, and drug specificity of the high-affinity site in the striatal membranes from ...
H L, Komiskey   +3 more
openaire   +2 more sources

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

open access: yes, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Zammit, Christian   +12 more
core  

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