Results 11 to 20 of about 2,841 (216)

Effects of 12-week Endurance Exercise on Dopamine Receptor Protein Expression in Hippocampus of Obese Rat [PDF]

open access: yes운동과학, 2020
PURPOSE The purpose of this study was to investigate changes of body composition, D1 dopamine receptors (D1DR), and D2 dopamine receptors (D2DR) protein expression after 12 weeks of moderate-intensity treadmill exercise in hippocampus of high fat diet ...
Sungwook Kim, Kijin Kim
doaj   +1 more source

Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice.

open access: yesPLoS ONE, 2013
Dopamine regulates the psychomotor stimulant activities of amphetamine-like substances in the brain. The effects of dopamine are mediated through five known dopamine receptor subtypes in mammals.
Seiji Hayashizaki   +8 more
doaj   +1 more source

Dopamine Modulates Drosophila Gut Physiology, Providing New Insights for Future Gastrointestinal Pharmacotherapy

open access: yesBiology, 2021
Dopamine has a variety of physiological roles in the gastrointestinal tract (GI) through binding to Drosophila dopamine D1-like receptors (DARs) and/or adrenergic receptors and has been confirmed as one of the enteric neurotransmitters.
Samar El Kholy   +3 more
doaj   +1 more source

Dopamine D4 Receptors

open access: yesJapanese Journal of Pharmacology, 2000
Initial investigations on dopamine D4 receptors generated much interest in the role of this receptor in schizophrenia and other aspects of human behavior, as well as new opportunities for novel therapeutics. However, attempts to treat patients suffering from schizophrenia with dopamine D4 agents have failed to yield satisfactory results so far.
M. Helmeste, Daiga, Wa Tang, Siu
openaire   +3 more sources

REDUCED EXPRESSION OF DOPAMINE D2-RECEPTORS ON PERIPHERAL BLOOD LYMPHOCYTES AS A MARKER FOR PROGRESSION OF SUBCORTICAL COGNITIVE IMPAIRMENTS

open access: yesZaporožskij Medicinskij Žurnal, 2013
Introduction. Peripheral blood lymphocytes (PBL) express neurotransmitter and neuropeptide receptors. The dopamine receptors in PBL may reflect the status of homologous brain receptors.
O. A. Levada   +2 more
doaj   +1 more source

A Concise Review of the Conflicting Roles of Dopamine-1 versus Dopamine-2 Receptors in Wound Healing

open access: yesMolecules, 2017
Catecholamines play an important regulatory role in cutaneous wound healing. The exact role of dopamine in human epidermis has yet to be fully elucidated. Current published evidence describes its differential effects on two separate families of G protein
Alexandra R. Vaughn   +3 more
doaj   +1 more source

Desensitized D2 autoreceptors are resistant to trafficking

open access: yesScientific Reports, 2017
Dendritic release of dopamine activates dopamine D2 autoreceptors, which are inhibitory G protein-coupled receptors (GPCRs), to decrease the excitability of dopamine neurons.
Brooks G. Robinson   +7 more
doaj   +1 more source

Voltage-Dependent Dopamine Potency at D1-Like Dopamine Receptors

open access: yesFrontiers in Pharmacology, 2020
In recent years, transmembrane voltage has been found to modify agonist potencies at several G protein-coupled receptors (GPCRs). Whereas the voltage sensitivities of the Gαi/o-coupled dopamine D2-like receptors (D2R, D3R, D4R) have previously been ...
Richard Ågren   +3 more
doaj   +1 more source

Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain. [PDF]

open access: yesPLoS ONE, 2012
The dopamine D(1), D(2), D(3) receptors, vesicular monoamine transporter type-2 (VMAT2), and dopamine transporter (DAT) densities were measured in 11 aged human brains (aged 77-107.8, mean: 91 years) by quantitative autoradiography.
Jianjun Sun   +4 more
doaj   +1 more source

Dopamine D2 receptors and the circadian clock reciprocally mediate antipsychotic drug-induced metabolic disturbances

open access: yesnpj Schizophrenia, 2017
Antipsychotic drugs are widely prescribed medications, used for numerous psychiatric illnesses. However, antipsychotic drugs cause serious metabolic side effects that can lead to substantial weight gain and increased risk for type 2 diabetes.
Zachary Freyberg, Michael J. McCarthy
doaj   +1 more source

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