Results 1 to 10 of about 147,933 (225)

Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV. [PDF]

J Neuroinflammation
The catecholamine neurotransmitter dopamine is classically known for regulation of central nervous system (CNS) functions such as reward, movement, and cognition. Increasing evidence also indicates that dopamine regulates critical functions in peripheral
Matt SM, Nolan R, Manikandan S, Agarwal Y, Channer B, Oteju O, Daniali M, Canagarajah JA, LuPone T, Mompho K, Runner K, Nickoloff-Bybel E, Li B, Niu M, Schlachetzki JCM, Fox HS, Gaskill PJ.   +16 more
europepmc   +4 more sources

Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users. [PDF]

Molecular Psychiatry, 2015
Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors influence amphetamine-induced dopamine release and that dopamine is involved in ...
Dean, AC, Kohno, M, London, ED, Mandelkern, MA, Morales, AM, Robertson, CL   +5 more
core   +5 more sources

Dopamine, the dopamine D2 receptor and pituitary tumours [PDF]

Clinical Endocrinology, 1991
Dopamine plays an important role in the hypothalamic-pituitary axis where its major effects are to inhibit pituitary hormone secretion and cell division. Chronic dopamine deficiency has been postulated as a cause of pituitary tumour formation and several lines of evidence exist to suggest that a functional deficiency may develop as a result of ...
D. F. Wood, Jane M. Johnston, Desmond G. Johnston   +2 more
openaire   +2 more sources

Dopamine receptors in GtoPdb v.2023.1 [PDF]

, 2023
Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [373]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is ...
Beaulieu, Jean-Martin, Borrelli, Emiliana, Carlsson, Arvid, Caron, Marc G., Civelli, Olivier, Espinoza, Stefano, Fisone, Gilberto, Gainetdinov, Raul R., Grandy, David K., Kebabian, John W., Langer, Saloman Z., Missale, Maria Cristina, Neve, Kim A., Scatton, Bernard, Schwartz, Jean-Charles, Sedvall, Goran, Seeman, Philip, Sibley, David R., Sokoloff, Pierre, Spano, Pierre F., Van Tol, Hubert H. M.   +20 more
core   +2 more sources

Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice [PDF]

, 2008
Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific dopamine receptor subtypes has not
Atkins, Baik, Battisti, Battisti, Boileau, Cador, Chiang, Crabbe, Crawford, de Wit, Down, Fleckenstein, Gabbay, Glickstein, Hamamura, Jones, Kalivas, Kamens, Karler, Karper, Kelly, Kelly, Kilty, Kuczenski, Kuribara, Kuribara, Kuribara, McDougall, Neve, Palmer, Phillips, Phillips, Pierce, Robinson, Ron, Rubinstein, Sax, Schmauss, Shen, Tanabe, Ujike, Vezina, Vezina, Xu, Xu, Xu, Xu, Yates   +47 more
core   +4 more sources

Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]

, 2020
Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S., Cardarelli, S., D'angelo, V., Fusco, F. R., Giorgi, M., Mercuri, N. B., Paldino, E., Sancesario, G., Sorge, R.   +8 more
core   +1 more source

D2 dopamine receptor gene and obesity [PDF]

International Journal of Eating Disorders, 1994
The prevalence of Taql A D2 dopamine receptor (DRD2) alleles was determined in 73 obese women and men. In this sample with a mean body mass index of 35.1, the A1 (minor) allele of the DRD2 gene was present in 45.2% of these nonalcohol, nondrug abusing subjects. The DRD2 A1 allele was not associated with a number of cardiovascular risk factors examined,
Terry Ritchie, Lorna A. Noble, Ernest P. Noble, Karl Syndulko, Rudolf E. Noble, Yzan Zhang, David K. Grandy, Robert S. Sparkes, M. Charlotte Bohlman   +8 more
openaire   +2 more sources

Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence. [PDF]

, 2016
BackgroundCigarette smoking induces dopamine release in the striatum, and smoking- or nicotine-induced ventral striatal dopamine release is correlated with nicotine dependence.
London, Edythe D, Mandelkern, Mark A, Okita, Kyoji   +2 more
core   +2 more sources

Purification of brain D2 dopamine receptor. [PDF]

The EMBO Journal, 1988
D2 dopamine receptors have been extracted from bovine brain using the detergent cholate and purified approximately 20,000-fold by affinity chromatography on haloperidol-sepharose and wheat germ agglutinin-agarose columns. The purified preparation contains D2 dopamine receptors as judged by the pharmacological specificity of [3H]spiperone binding to the
Williamson, RA, Worrall, S, Chazot, PL, Strange, PG   +3 more
openaire   +3 more sources

Stress-induced reduction of dorsal striatal D2 dopamine receptors prevents retention of a newly acquired adaptive coping strategy [PDF]

, 2017
The inability to learn an adaptive coping strategy in a novel stressful condition leads to dysfunctional stress coping, a marker of mental disturbances.
Cabib, Simona, Campus, Paolo, Canterini, Sonia, Fiorenza, Maria Teresa, Orsini, Cristina, PUGLISI ALLEGRA, Stefano   +5 more
core   +1 more source