Results 21 to 30 of about 751,516 (267)

D2 dopamine receptor subtype-mediated hyperactivity and amphetamine responses in a model of ADHD

Neurobiology of Disease, 2010
Low doses of psychostimulants produce beneficial behavioral effects in ADHD patients but the mechanisms underlying the response are not understood. Here we use the hyperactive mouse mutant coloboma to identify D2-like dopamine receptor subtypes that ...
Xueliang Fan, Ming Xu, Ellen J. Hess
doaj   +1 more source

Antisera specific for D2 dopamine receptors [PDF]

Biochemical Journal, 1993
Antisera have been raised against two peptides from the sequence of D2 dopamine receptors: peptide 1 from the predicted second extracellular loop and peptide 2 from the predicted third intracellular loop. The antisera recognize specifically a 95 kDa band in Western blots of several bovine brain regions, which corresponds to the denatured D2 dopamine ...
P L, Chazot, A J, Doherty, P G, Strange
openaire   +2 more sources

Dopaminergic modulation of odor responses by local interneurons in the olfactory bulb [PDF]

, 2011
The olfactory bulb is one of the few regions in the brain where dopamine is provided locally by an intrinsic population of GABAergic interneurons but their role in processing of sensory information remains ambiguous.
Bundschuh, Sebastian Tylman
core   +1 more source

In Vitro and In Vivo Characterization of PCC0104005, a Novel Modulator of Serotonin-Dopamine Activity, as an Atypical Antipsychotic Drug

Scientific Reports, 2018
PCC0104005 is a novel drug candidate for treating schizophrenia that displays high affinity for serotonin, dopamine, and noradrenaline receptors, including partial agonism at dopamine D2, D3, D4, serotonin 5-HT1A, and 5-HT2A receptors and antagonism at 5-
Yanan Xu, Xiaoyin Zhu, Hongbo Wang, Shanyue Sun, Xin Yue, Jingwei Tian   +5 more
doaj   +1 more source

Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons

European Journal of Histochemistry, 2014
Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structure of the adult rat arcuate-median eminence complex, and determine the distribution of the dopamine D1 and D2 receptor immunoreactivities therein ...
W. Romero-Fernandez, D.O. Borroto-Escuela, V. Vargas-Barroso, M. Narváez, M. Di Palma, L.F. Agnati, J. Larriva Sahd, K. Fuxe   +7 more
doaj   +1 more source

Pharmacological Evidence That Dopamine Inhibits the Cardioaccelerator Sympathetic Outflow via D2-Like Receptors in Pithed Rats

Journal of Pharmacological Sciences, 2013
It has been suggested that N,N-di-n-propyl-dopamine (dopamine analogue) decreased heart rate in rats through stimulation of dopamine receptors. Nevertheless, the role of prejunctional dopamine D1/2-like receptors or even α2-adrenoceptors to mediate ...
Oscar Alcántara-Vázquez, Ma. Trinidad Villamil-Hernández, Araceli Sánchez-López, David Centurión   +3 more
doaj   +1 more source

Dopamine regulates approach-avoidance in human sensation-seeking. [PDF]

, 2015
Background Sensation-seeking is a trait that constitutes an important vulnerability factor for a variety of psychopathologies with high social cost.
Roiser, JP, Winston, J., Roiser, J., Kurth-Nelson, Z, Husain, M., Kurth-Nelson, Z. ; https://orcid.org/, Norbury, A, Husain, M, ,, Norbury, A., Winston, JS   +10 more
core   +1 more source

Prefrontal and striatal dopamine D2/D3 receptors correlate with fMRI BOLD activation during stopping [PDF]

, 2021
D2-like dopamine receptors in animals and humans have been shown to be linked to impulsive behaviors that are highly relevant for several psychiatric disorders.
Kaller, Christoph P., Tüscher, Oliver, Schreckenberger, Mathias, Buchholz, Hans Georg, Pfeifer, Philippe, Gründer, Gerhard, Fehr, Christoph, Sebastian, Alexandra   +7 more
core   +2 more sources

Two dopamine D2-like receptor genes from the silkworm (Bombyx mori) and their evolutionary history in metazoan

Scientific Reports, 2017
Dopamine is widely distributed in metazoans and is implicated in many physiological functions. Dopaminergic signaling is mediated through two classes of dopamine receptors, D1-like and D2-like.
Ping Chen, Peng Chen, Tian Li, Qi Shen, Deng-Feng Yan, Liang Zhang, Xi Chen, Yan Li, Wei Zhao   +8 more
doaj   +1 more source

Structure and Function Studies of the Human Dopamine Receptors [PDF]

, 2004
Dopamine neurotransmitter and its receptors play a critical role in cell signaling process responsible for information transfer in neurons functioning in the nervous system.
Kalani, M. Yashar S.
core   +1 more source