Results 111 to 120 of about 751,516 (267)

Modulatory Effects of Dopamine D2 Receptors on Spreading Depression in Rat Somatosensory Neocortex

open access: yesBasic and Clinical Neuroscience, 2014
Introduction: Spreading depression (SD) is a propagating wave of depolarization followed by depression of the neuroglial activities and can modulate extracellular dopamine concentrations in the neocortex.
Anna Maria Haarmann   +3 more
doaj  

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer   +4 more
wiley   +1 more source

Heterodimeric D1-D2 dopamine receptors: a review

open access: yes, 2017
This review summarizes modern data on the structure and functions ofheteromersformed by D1 and D2 dopamine receptors focusing on their role in the mechanisms of drug dependence.
I.Yu. Shamakina   +3 more
core   +1 more source

Trait Neuroticism and the Nocebo Effect: The Mediating Role of Side‐Effect Expectations

open access: yesJournal of Personality, EarlyView.
ABSTRACT Objective Neuroticism has not only been linked to heightened negative expectations and general somatic complaints but also to increased nocebo responses following medical treatments. Since side‐effect expectations are considered a main driver of nocebo responses, we tested whether side‐effect expectations mediate the neuroticism–nocebo ...
Anton Fischer   +4 more
wiley   +1 more source

Dietary L‐Tyrosine Sustains Egg Production and Quality by Modulating Promoter CpG Methylation, Gene Expression, and Hormone Profiles in Reproductive Signalling Pathways of Aged Laying Hens

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Managing prolactin (PRL)‐mediated reproductive suppression is critical for maintaining egg production in commercial laying hens. L‐tyrosine (TYR), a precursor of dopamine (DA), may counteract age‐related reproductive decline by suppressing PRL, thereby sustaining productivity and egg quality in late‐phase laying hens.
Hasan Hüseyin İpçak
wiley   +1 more source

Chronic treatment with dopamine receptor antagonists: behavioral and pharmacologic effects on D1 and D2 dopamine receptors

open access: yes, 1988
Rats were treated for 21 d with the selective D1 dopamine receptor antagonist SCH23390, the selective D2 dopamine receptor antagonist spiperone, the nonselective dopamine receptor antagonist cis- flupentixol, or a combination of SCH23390 and spiperone ...
EJ Hess, AB Norman, I Creese
core   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet   +8 more
wiley   +1 more source

The Relationship Between Resting State Quantitative EEG and Daytime Sleepiness Complaints in Parkinson's Disease

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Although many studies have reported the presence of daytime sleepiness in Parkinson's disease (PD), either a weak or no association has been found between self‐reported and current objective measures of daytime sleepiness in this population. Changes in resting state quantitative electroencephalography (qEEG) have been associated with increased
Thaïna Rosinvil   +5 more
wiley   +1 more source

Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung   +4 more
wiley   +1 more source

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