Results 121 to 130 of about 150,460 (322)
Dopamine controls various physiological functions in the brain and periphery by acting on its receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors involved in the regulation of motor activity and several neurological ...
A. Mishra, Sonu Singh, S. Shukla
semanticscholar +1 more source
Antipsychotic Drugs Influence Dopamine Neuron Terminals via Action on D2-receptors and Vesicles [PDF]
Undergraduate Denman Research Forum - 2nd PlaceDopamine D2 antagonist antipsychotic drugs share the effects of increasing dopamine synthesis, dopamine neuron firing rate, and dopamine and DOPAC levels. These antagonists all raise extracellular dopamine
Klausing, Alex
core
Abstract Background Restless Legs Syndrome (RLS) is a neurological disorder reported to be associated with impulsivity and impairments in interoception and emotional regulation. However, limited research has explored the combined influence of RLS severity, psychological factors, and chronotype on impulsive decision‐making and risk‐taking behavior in ...
Giacomo Carollo+5 more
wiley +1 more source
RationaleFew studies have investigated neurobiological and biochemical differences between stress-resilient and stress-vulnerable experimental animals.ObjectivesWe investigated alterations in mesolimbic dopamine D2 receptor density and mRNA expression ...
D. Żurawek+6 more
semanticscholar +1 more source
The regulation of D2 dopamine receptor expression [PDF]
The question of whether or not there is a polymorphism in or near DRD2 which is associated with receptor density remains unanswered. Both clinical and animal data demonstrate that D 2 dopamine receptor density is highly variable among individuals; differences of more than 100% are not uncommon. Among inbred mouse strains and F 2 intercrosses produced
openaire +2 more sources
Safety and Effect of 12‐Month Ecopipam Treatment in Pediatric Patients with Tourette Syndrome
Abstract Background Tourette syndrome (TS) is a chronic neurodevelopmental tic disorder with a considerable quality of life (QOL) burden. Objectives The goal was to determine the long‐term safety, tolerability, and clinical effects of ecopipam, a first‐in‐class dopamine D1 receptor antagonist, for TS.
Donald L. Gilbert+7 more
wiley +1 more source
Tetrahydrocannabinol and dopamine D1 receptor
Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family. The D1
Jiwon Lee
doaj +1 more source
The amygdala, a critical structure for both Pavlovian fear conditioning and fear extinction, receives sparse but comprehensive dopamine innervation and contains dopamine D1 and D2 receptors.
Yan-Wei Shi+10 more
doaj +1 more source
Abstract Background Evidence suggests that female gender represents a risk factor for the development of motor/nonmotor fluctuations and dyskinesia in Parkinson's disease (PD). So far, no prospective study has analyzed this aspect in relation to the introduction of levodopa treatment.
Maria Teresa Pellecchia+41 more
wiley +1 more source
Management of Anxiety in Parkinson's Disease
ABSTRACT Background Anxiety is a common, distressing, hard‐to‐diagnose and hard‐to‐treat symptom in Parkinson's disease. No formal guidelines exist to assist management. Objective We provide a pragmatic guide to detecting and managing anxiety in Parkinson's disease.
Alex J. Berry+4 more
wiley +1 more source