Results 121 to 130 of about 39,913 (215)

Population Pharmacokinetic Model‐Based Dose Selection of Extended‐Release Injectable Olanzapine (TV‐44749) for Subcutaneous Use in Phase 3 Clinical Trial in Adults with Schizophrenia

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract TV‐44749 is a long‐acting subcutaneous (SC) injectable olanzapine based on a novel copolymer drug delivery technology ensuring controlled olanzapine release over the dosing interval. TV‐44749's formulation and SC route of administration aim to eliminate the causes of post‐injection delirium/sedation syndrome (PDSS) that may occur with the ...
Itay Perlstein, Irina Cherniakov, Anna Elgart, Roberto Gomeni, Dikla Gutman, Avia Merenlender Wagner, Rajendra Singh   +6 more
wiley   +1 more source

What is the Impact of Dopamine D2 Receptor in the Brain-Gut Axis? A Narrative Review of the Mechanism Based on Gut Microbiota in Modulating Emotion and Behavior. [PDF]

Alpha Psychiatry
Xie YA, Kong JD, Li S, Wei DF.
europepmc   +1 more source

Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity

Lifestyle Medicine, Volume 7, Issue 1, January 2026.
ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien, Sylvester Ifeanyi Omoruyi, Brendon Pearce, Melisse Erasmus, Nireshni Chellan   +4 more
wiley   +1 more source

(-)-OSU6162 reduces freezing elicited by context-conditioned fear in rats. [PDF]

J Psychopharmacol
Atanasovski D, Hagsäter SM, Myrehag M, Arheden K, Sjöblad S, Eriksson E.   +5 more
europepmc   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 69-106, January/February 2026.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

A Hypersexuality Subset Behavior Induced by Aripiprazole Overdose in an Antipsychotic Naïve Patient: A Case Report and Review of the Literature. [PDF]

Clin Pract
Serfilippi T, Piccirillo S, Preziuso A, Terenzi V, Romagnoli F, Tarini M, Lariccia V, Secondo A, Magi S.   +8 more
europepmc   +1 more source

Subcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS‐Park Cohort

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 142-153, January 2026.
Abstract Background Impulse control disorders (ICD) are common non‐motor complications in Parkinson's disease (PD), particularly in patients receiving oral dopamine agonists (DA). Continuous subcutaneous apomorphine infusion (CSAI) is a device‐aided therapy for advanced PD, but its effects on ICD remain underexplored in real‐world settings.
Clément Desjardins, Paulo André Dias Bastos, Aymeric Lanore, Christine Brefel‐Courbon, Isabelle Benatru, Caroline Giordana, Anne Doe de Maindreville, Giovanni Castelnovo, Philippe Remy, Luc Defebvre, Claire Thiriez, Stéphane Prange, Jean‐Luc Houeto, Alexandra Samier Foubert, Fabienne Ory‐Magne, Raquel Pinhero Barbosa, Nathalie Bertille, Jean‐Christophe Corvol, Olivier Rascol, Margherita Fabbri, on behalf of the NS‐Part Cohort study group, Jean‐Christophe Corvol, Olivier Rascol, Margherita Fabbri, Wassilios Meissner, Stéphane Thobois, Luc Defebvre, Helene Esperou, Florence Tubach, Yann De Rycke, Layidé Roufai, Dalila Ouazib, Sandra Zarrad, Fatma Khelifi, Florence Tubach, Yann De Rycke, Nathalie Bertille, Vanessa Rousseau, Samuel Tessier, Margherita Fabbri, David Tavel, Dounya Metdaoui, Avigaelle Abitbol, Mathias Antunes, Alexis Brice, Suzanne Lesage, Christelle Tessson, Fanny Casse, Mélanie Ferrien, Guillaume Cogan, Lisa Welment, Thierry Moulin, Wassilios Meissner, Claire Thiriez, Stéphane Thobois, Christian Geny, Solène Frismand, Anne‐Gaëlle Corbille, Caroline Giordana, Giovanni Castelnovo, Isabelle Benatru, Sophie Drapier, David Maltete, Christine Tranchant, Olivier Rascol, Mickael Aubignat, Marie Mongin, Matthieu Bereau, Alexandra Foubert‐Samier, Brice Laurens, Sylvain Vergnet, Thomas Boraud, David Bendetowicz, Jade Sarrabere, Dominique Guehl, Pierre Burbaud, Paul‐Alexandre Pfeiffer, Gilles Defer, Bérengère Debilly, Philippe Derost, Alice Dormeuil, Aimée Petit, Alban Gravier, Vincent Schneider, Lucie Garnier, Nicolas Carriere, Olivier Colin, Philippe Couratier, Chloé Laurencin, Stephane Prange, Paul Jaulent, Bruno Plus, Helene Gervais‐Bernard, Alexandre Eusebio, Frédérique Fluchere, Stephan Grimaldi, Valentin Mira, Tatiana Witjas, Mahmoud Charif, Ophelie Forster, Alix Durand, Pauline Prin, Lucie Hopes, Amory Jardel, Salome Puisieux, Guillemette Clement, Philippe Damier, Tiphaine Rouaud, Pascal Derkinderen, Arthur Lionnet, Adrien De Guilhem De Lataillade, Cosmin Alecu, Charlotte Heraud, Marie De Verdal, Graziella Mangone, Sara Sambin, Aymeric Lanore, Thomas Courtin, Louise‐Laure Mariani, Fouad Khoury, Poornima Menon, Florence Cormier‐Dequaire, Emmanuel Flamand‐Roze, David Grabli, Elodie Hainque, Marie Vidhaillet, Aurélie Meneret, Cécile Delorme, Cendrine Foucard, Florian Von Raison, Alexis Elbaz, Andreas Hartmann, Vincent Leclercq, Theodore Soulier, Daniel Torres, Giulia Coarelli, Giorgia Querin, Fabien Hauw, Margaux Dunoyer, Solène Ansquer, Frederique Leh, Marion Leclercq, Simon Lamy, Guillaume Carey, Guillaume Costentin, Clemence Hardy, Mathieu Anheim, Ouhaid Lagha Boukbiza, Thomas Wirth, Jimmy Voirin, Marie Des Neiges Santin, Thomas Bogdan, Margherita Fabbri, Christine Brefel Courbon Ory‐Magne, Clemence Leung, Hélène Catala, Gabrielle Sill, Raquel Pinheiro Barbosa, Lucy Famer, Lucie Braccagni, Hiba Sifaoui, Juliette Palisson, Kenza Benrahmoune Idrissi, Astrid Causel, Lydie Romeo, Constance Bissessur, Audace Cure‐Martin, Charline Compagne, Sandrine Dupouy, Sandrine Villars, Wei‐Ho Lai, Rachida Bari, Damien Chevanne, Elodie Durand, Isabelle Rieu, Stephane Bernard, Corinne Garsault, Nathalie Meunier, Alexia Cresson, Marine Sgard, Marie Dreano, Justine Montillot, Renaud Massart, Pascale Grebent, Pierre Pelissier, Valérie Santraine, Thomas Gaudin, Pierre Boutet, Cécile Thuilier, Coralie Chalot, Céline Prevost, Hélène Videaud, Justine Picut, Christian Tarrade, Catherine Caire, Hélène Merle, Elise Metereau, Mathilde Millot, Chloe Bernardi, Emilie Favre, Adelaide Jaulent, Laura Mundler, Blandine Dufresne, Eve Benchetrit, Valérie Driss, Alexia Arifi, Maura Rodrigues, Lili Le Monnier, Nathalie Dumont, Virginie Bablon, Régis Frenais, Caroline Herve, Christelle Guimber, Vanessa Ferrier, Elodie David, Christina Faroul, Leslie Fra, Elsa Foucaran, Fatima‐Ezzahra Ennaji, Jeremy Bonetto, Ryad Ladghem‐Chikouche, Le Mickael, Sophie Liot, Sonia Messar, Hamza Salah, Amelie Bernardo, Naoual Serari, Emilie Rabois, Carole David, Zoe Fournier, Margaux Bonnaire‐Verdier, Elise Chevaillier, Françoise Kestens, Rozenn Gourhan, Sandra Lopez‐Alfaro, Jean‐François Houvenaghel, Mélanie Alexandre, Christine Bourdonnais, Linda Vernon, Ahmed Boumediene, Hugo Rummel, Céline Julie, Nadine Longato, Célie Phillipps, Anne Claire Andries‐Ros, Stéphanie Bras, Estelle Harroch, Claudia Gillet, Yoan Herades, Eva Camgrand   +249 more
wiley   +1 more source

Functional neuroanatomy of dopaminergic arousal systems: implications for the wake-promoting effect of psychostimulants, with particular reference to modafinil. [PDF]

Front Neuroanat
Szabadi E.
europepmc   +1 more source

Dopamine D2 Receptor Dimer Formation [PDF]

Journal of Biological Chemistry, 2001
Duncan Armstrong, Philip G. Strange
openaire   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
wiley   +1 more source